Diabate A. auteur aut IRD Brengues Cécile auteur aut IRD Baldet T. auteur aut IRD Dabiré K.R. auteur aut IRD Hougard Jean-Marc auteur aut IRD Akogbeto M. auteur aut IRD Kengne Pierre auteur aut IRD Simard Frédéric auteur aut IRD Guillet Pierre auteur aut IRD Hemingway J. auteur aut IRD Chandre Fabrice auteur aut IRD text journalArticle eng text/pdf reformatted digital access During extensive sampling in Burkina Faso and other African countries, the Leu‐Phe mutation producing the kdr pyrethroid resistance phenotype was reported in both Anopheles gambiae ss and A. arabiensis. This mutation was widely distributed at high frequency in the molecular S form of A. gambiae while it has been observed at a very low frequency in both the molecular M form and A. arabiensis in Burkina Faso. While the mutation in the M form is inherited through an introgression from the S form, its occurrence is a new and independent mutation event in A. arabiensis. Three nucleotides in the upstream intron of the kdr mutation differentiated A. arabiensis from A. gambiae ss and these specific nucleotides were associated with kdr mutation in A. arabiensis. Ecological divergences which facilitated the spread of the kdr mutation within the complex of A. gambiae ss in West Africa, are discussed. PALUDISME MOUSTIQUE INSECTICIDE CHIMIQUE RESISTANCE DE L'HOTE MUTATION POLYMORPHISME GENETIQUE ANALYSE GENETIQUE INTROGRESSION PYRETHROIDE TECHNIQUE PCR AFRIQUE BURKINA FASO 052ANOPAL04 9 12 1267-1273 2004 1360-2276 https://www.documentation.ird.fr/hor/fdi:010034589 1360-2276 [F B010034589] https://www.documentation.ird.fr/hor/fdi:010034589 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-10/010034589.pdf IRD - Base Horizon / Pleins textes 2020-10-15 2020-11-12 fdi:010034589 fre