@article{fdi:010034589, title = {{T}he spread of the {L}eu‐{P}he kdr mutation through {A}nopheles gambiae complex in {B}urkina {F}aso : genetic introgression and de novo phenomena}, author = {{D}iabate, {A}. and {B}rengues, {C}{\'e}cile and {B}aldet, {T}. and {D}abir{\'e}, {K}.{R}. and {H}ougard, {J}ean-{M}arc and {A}kogbeto, {M}. and {K}engne, {P}ierre and {S}imard, {F}r{\'e}d{\'e}ric and {G}uillet, {P}ierre and {H}emingway, {J}. and {C}handre, {F}abrice}, editor = {}, language = {{ENG}}, abstract = {{D}uring extensive sampling in {B}urkina {F}aso and other {A}frican countries, the {L}eu‐{P}he mutation producing the kdr pyrethroid resistance phenotype was reported in both {A}nopheles gambiae ss and {A}. arabiensis. {T}his mutation was widely distributed at high frequency in the molecular {S} form of {A}. gambiae while it has been observed at a very low frequency in both the molecular {M} form and {A}. arabiensis in {B}urkina {F}aso. {W}hile the mutation in the {M} form is inherited through an introgression from the {S} form, its occurrence is a new and independent mutation event in {A}. arabiensis. {T}hree nucleotides in the upstream intron of the kdr mutation differentiated {A}. arabiensis from {A}. gambiae ss and these specific nucleotides were associated with kdr mutation in {A}. arabiensis. {E}cological divergences which facilitated the spread of the kdr mutation within the complex of {A}. gambiae ss in {W}est {A}frica, are discussed.}, keywords = {{PALUDISME} ; {MOUSTIQUE} ; {INSECTICIDE} {CHIMIQUE} ; {RESISTANCE} {DE} {L}'{HOTE} ; {MUTATION} ; {POLYMORPHISME} {GENETIQUE} ; {ANALYSE} {GENETIQUE} ; {INTROGRESSION} ; {PYRETHROIDE} ; {TECHNIQUE} {PCR} ; {AFRIQUE} ; {BURKINA} {FASO}}, booktitle = {}, journal = {{T}ropical {M}edicine and {I}nternational {H}ealth}, volume = {9}, numero = {12}, pages = {1267--1273}, ISSN = {1360-2276}, year = {2004}, URL = {https://www.documentation.ird.fr/hor/fdi:010034589}, }