@article{fdi:010032994,
  title = {{G}enetic diversity and population structure of {M}ycobacterium tuberculosis in {C}asablanca, a {M}oroccan city with high incidence of tuberculosis},
  author = {{T}azi, {L}oubna and {E}l {B}aghdadi, {J}. and {L}esjean, {S}. and {L}ocht, {C}. and {S}upply, {P}. and {T}ibayrenc, {M}ichel and {B}anuls, {A}nne-{L}aure},
  editor = {},
  language = {{ENG}},
  abstract = {{A}lthough lower-resource countries have by far the highest burden of tuberculosis, knowledge of {M}ycobacterium tuberculosis population structure and genetic diversity in these regions remains almost nonexistent. {I}n this paper, 150 {M}oroccan {M}. tuberculosis isolates circulating in {C}asablanca were genotyped by random amplified polymorphic {DNA} analysis using 10 different primers and by mycobacterial interspersed repetitive units-variable number of tandem repeats typing at 12 loci. {T}he population genetic tests revealed a basically clonal structure for this population, without excluding rare genetic exchanges. {G}enetic analysis also showed a notable genetic polymorphism for the species {M}. tuberculosis, a weak cluster individualization, and an unexpected genetic diversity for a population in such a high-incidence community. {P}hylogenetic analyses of this {M}oroccan sample also supported that these isolates are genetically heterogeneous.},
  keywords = {{BACTERIE} ; {STRUCTURE} {DE} {POPULATION} ; {POLYMORPHISME} {GENETIQUE} ; {PHYLOGENIE} ; {TUBERCULOSE} ; {DIVERSITE} {GENETIQUE} ; {TECHNIQUE} {RAPD} ; {MARQUEUR} {MOLECULAIRE} ; {ANALYSE} {GENETIQUE} ; {MAROC} ; {CASABLANCA}},
  booktitle = {},
  journal = {{J}ournal of {C}linical {M}icrobiology},
  volume = {42},
  numero = {1},
  pages = {461--466},
  ISSN = {0095-1137},
  year = {2004},
  DOI = {10.1128/{JCM}.42.1.461-466.2004},
  URL = {https://www.documentation.ird.fr/hor/fdi:010032994},
}