@article{fdi:010030651, title = {{KDR} mutation, a genetic marker to assess events of introgression between the molecular {M} and {S} forms of {A}nopheles gambiae ({D}iptera: {C}ulicidae) in the tropical savannah area of {W}est {A}frica}, author = {{D}iabate, {A}. and {B}aldet, {T}hierry and {C}handre, {F}abrice and {D}abire, {K}.{R}. and {K}engne, {P}ierre and {G}uiguembe, {T}.{R}. and {S}imard, {F}r{\'e}d{\'e}ric and {G}uillet, {P}ierre and {H}emingway, {J}. and {H}ougard, {J}ean-{M}arc}, editor = {}, language = {{ENG}}, abstract = {{A} sodium channel 'kdr'-type mutation was identified in the {M} form of {A}nopheles gambiae from {B}urkina {F}aso in the tropical savannah area belt. {T}he molecular {M} form of {A}n. gambiae is found at high frequencies in the flooded rice cultivation area of {K}ou {V}alley, where the insecticide selection pressure is limited. {T}he spread of the mutation in the {M} population is an ongoing process, as it increased from a frequency of 0.006 in 1999 to 0.02 in 2000. {T}he {S} molecular form occurs in sympatry in our study village, with the {M} form at a relatively low frequency. {T}he common 'kdr' mutation was previously detected in this area in the {S} form, and has probably invaded the {M} population through genetic introgression. {T}his impacts on the question of actual levels of gene flow between the two molecular forms in tropical savannah areas. {A} hybrid {M}/{S} individual was identified during the course of this study, which was homozygous for the 'kdr' mutation. {P}yrethroid resistant {A}n. gambiae were caught in {O}ctober and {N}ovember, which is the time of year that the molecular {S} form migrates into this area as rain-fed breeding sites in the cotton fields dry out.}, keywords = {{PALUDISME} ; {VECTEUR} ; {MOUSTIQUE} ; {MUTATION} ; {INSECTICIDE} {CHIMIQUE} ; {SENSIBILITE} {RESISTANCE} ; {ANALYSE} {GENETIQUE} ; {VARIATION} {SAISONNIERE} ; {SAVANE} ; {PERMETHRINE} ; {MUTATION} {KDR} ; {ZONE} {TROPICALE} ; {BURKINA} {FASO} ; {KOU} {VALLEE}}, booktitle = {}, journal = {{J}ournal of {M}edical {E}ntomology}, volume = {40}, numero = {2}, pages = {195--198}, ISSN = {0022-2585}, year = {2003}, DOI = {10.1603/0022-2585-40.2.195}, URL = {https://www.documentation.ird.fr/hor/fdi:010030651}, }