@article{fdi:010027848,
  title = {{R}elationships between the prevalence and intensity of {L}oa loa infection in the {C}entral province of {C}ameroon},
  author = {{B}oussinesq, {M}ichel and {G}ardon, {J}. and {K}amgno, {J}. and {P}ion, {S}.{D}.{S}. and {G}ardon-{W}endel, {N}. and {C}hippaux, {J}ean-{P}hilippe},
  editor = {},
  language = {{ENG}},
  abstract = {{I}vermectin treatment may induce marked adverse effects in those harbouring > 8000 {L}oa microfilariae (mff)/ml of blood, individuals with > 30 000 {L}oa mff/ml being at risk of developing serious neurological reactions. {I}t is thus necessary to delineate the geographical areas where such responses may occur. {T}o determine if the simple measure of prevalence of {L}oa microfilaraemia would be appropriate to identify the communities at risk, the relationships between prevalence and intensity of {L}oa microfilaraemia were investigated in 67 villages in {C}ameroon. {T}he prevalence recorded in the adult population was found to be closely related to each of the indicators of infection intensity investigated. {F}or example, when the prevalences of {L}oa microfilaraemia in adults were 20%, 30% and 40%, approximately 5%, 9% and 16% of the adults had microfilarial loads exceeding 8000 mff/ml, respectively; the corresponding percentages of adults with > 30 000 mff/ml were about 1%, 3% and 5%-6%. {T}hus it seems that, in areas where loiasis is co-endemic, the monitoring procedure during large-scale ivermectin treatments for the control of onchocerciasis only needs to be strengthened in those communities where the prevalence of {L}oa microfilaraemia in adults exceeds 20%},
  keywords = {{ONCHOCERCOSE} ; {LOASE} ; {TRAITEMENT} {MEDICAL} ; {PREVALENCE} ; {ETUDE} {COMPARATIVE} ; {INVERMECTINE} ; {CHIMIOPROPHYLAXIE} {DE} {MASSE} ; {EFFET} {INDESIRABLE} ; {MICROFILAREMIE} ; {FACIES} {EPIDEMIOLOGIQUE} ; {INTENSITE} ; {CAMEROUN} ; {LEKIE} ; {MBAM}},
  booktitle = {},
  journal = {{A}nnals of {T}ropical {M}edicine and {P}arasitology},
  volume = {95},
  numero = {5},
  pages = {495--507},
  ISSN = {0003-4983},
  year = {2001},
  DOI = {10.1080/00034980120073184},
  URL = {https://www.documentation.ird.fr/hor/fdi:010027848},
}