@article{fdi:010025997, title = {{S}tudies on the macrofilarial population of {O}nchocerca volvulus in hyper-endemic villages of the {C}entral province of {C}ameroon}, author = {{B}oussinesq, {M}ichel and {G}ardon, {J}acques and {K}amgno, {J}. and {D}emanga-{N}gangue, ... and {P}ion, {S}.{D}.{S}. and {D}uke, {B}.{O}.{L}.}, editor = {}, language = {{ENG}}, abstract = {{T}he population structure of #{O}nchocerca volvulus$ macrofilariae was studied in villages of central {C}ameroon where onchocerciasis is hyper-endemic. {O}ne nodule selected at random was removed from each of 576 adult males, and examined by histology. {T}he numbers of male and female worms/nodule, and the status of the female worms (fecund, non-fecund, or dead) were recorded. {T}he observations were analysed to evaluate whether the mean numbers of worms of each category varied in relation to the patient's age, the level of endemicity in his village, the anatomical localization of the nodule, the weight of the nodule, and the total number of palpable nodules harboured by the patient. {T}he results obtained were very similar to those reported from {W}est {A}frica. {T}he mean numbers of dead female worms/nodule were relatively high in the villages with the lowest levels of endemicity. {T}he mean numbers of fecund females and of live males were significantly higher in the nodules located around the knees. {T}hese results provide information which might be useful in modelling the population dynamics of #{O}. volvulus$, and also in the context of trials of any potentially macrofilaricidal drugs. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{ONCHOCERCOSE} ; {PARASITE} ; {HISTOLOGIE} ; {NODULE} ; {STRUCTURE} {DE} {POPULATION} ; {ENDEMIE} ; {AGE} {PHYSIOLOGIQUE} ; {METHODE} {DE} {LUTTE} ; {MEDICAMENT} ; {ETUDE} {COMPARATIVE} ; {IVERMECTINE} ; {CAMEROUN} ; {MBAM}}, booktitle = {}, journal = {{A}nnals of {T}ropical {M}edicine and {P}arasitology}, volume = {95}, numero = {4}, pages = {379--388}, ISSN = {0003-4983}, year = {2001}, DOI = {10.1080/00034980120064337}, URL = {https://www.documentation.ird.fr/hor/fdi:010025997}, }