@article{fdi:010025991,
  title = {{P}revalence and genetic variants of hepatitis {GB}-{C}/{HG} and {TT} viruses in {G}abon, {E}quatorial {A}frica},
  author = {{T}uveri, {R}. and {P}erret, {J}.{L}. and {D}elaporte, {E}ric and {N}guemby-{M}bina, {C}. and {R}evault d'{A}llones, {L}. and {H}enzel, {D}. and {F}aivre, {D}. and {S}carpa, {B}. and {C}ontu, {P}. and {C}olombo, {M}. and {T}hiers, {V}. and {B}r{\'e}chot, {C}. and {L}arouze, {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he distribution of {H}epatitis {GB}-{C}/{HG} ({GB}-{C}/{HG}) and {TT} viruses ({TTV}) infections was investigated in selected populations from {G}abon using {P}olymerase {C}hain {R}eaction ({PCR}) and {E}nzyme {L}inked {I}mmunosorbent {A}ssay ({ELISA}) for anti-{E}nvelop 2 (anti-{E}2) {GBV}-{C}/{HGV} {RNA} positive (+) and 32 of 81 (39.5%) anti-{E}2 + versus 8 of 39 (20.5%) {TTV} {DNA} +. {F}or tuberculosis patients, the figures were 11.5% (4/35) and 0%. {A} study of hepatocellular carcinoma cases (n = 27) versus controls (n = 66) did not show significant differences for {GBV}-{C}/{HGV} {RNA} (10.7% versus 12.1%) and {TTV} {DNA} (44.4% versus 30.3%). {A}ccording to phylogenetic analysis, the 15 {GBV}-{C}/{HGV} strains investigated clustered in group 1, the most common in sub-{S}aharan {A}frica whereas {TTV} sequences (n = 4) mostly clustered in genotypes {G}1 and one close to genotype {G}3. {I}n the {G}abonese populations investigated, {GBV}-{C}/{HGV} and {TTV} infections were highly endemic. {T}hese data are consistent with the low pathogenicity of these agents. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{MALADIE} ; {EPIDEMIE} ; {VIRUS} ; {INFECTION} ; {PREVALENCE} ; {DISTRIBUTION} ; {ANALYSE} {GENETIQUE} ; {METHODE} {D}'{ANALYSE} ; {TECHNIQUE} {PCR} ; {TEST} {ELISA} ; {PHYLOGENIE} ; {ETUDE} {EXPERIMENTALE} ; {ETUDE} {COMPARATIVE} ; {HEPATITE} ; {TUBERCULOSE} ; {GABON} ; {LIBREVILLE} ; {FRANCEVILLE}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {63},
  numero = {3,4},
  pages = {192--198},
  ISSN = {0002-9637},
  year = {2000},
  URL = {https://www.documentation.ird.fr/hor/fdi:010025991},
}