@article{fdi:010025682, title = {{I}dentification of a complex env subtype {E} {HIV} type 1 virus from the {D}emocratic {R}epublic of {C}ongo, recombinant with {A}, {G}, {H}, {J}, {K}, and unknown subtypes}, author = {{V}idal, {N}icole and {M}ulanga {K}abeya, {C}laire and {N}zilambi, {N}. and {D}elaporte, {E}ric and {P}eeters, {M}artine}, editor = {}, language = {{ENG}}, abstract = {{U}p to now, all known env subtype {E} viruses ({CRF}01-{AE}) have had the same mosaic structure with subtype {A}, and no other env subtype {E} {HIV}-1 viruses with non-{A} subtypes in their genomes have been described. {I}n this report, we describe the full-length genome sequence of an env subtype {E} isolate with a recombinant genome different from the prototype {CRF}01-{AE} strains. {T}he 97{CD}-{KTB}-49 strain, obtained from a tuberculosis patient in {K}inshasa, has a complex mosaic genome involving subtypes {A}, {E}, {G}, {H}, {J}, {K}, and several unknown fragments. {T}he {U} sequences formed well-separated clusters together with previously described unknown fragments from {CRF}04-cpx (subtype {I}), and from {Z}321, the oldest intersubtype recombinant isolated in 1976 in the {D}emocratic {R}epublic of {C}ongo. {T}he complex recombinant virus from our study is not an isolated strain ; partial sequencing of a second strain, 97{CD}-{KFE}45, confirmed the breakpoints observed in the 97{CD}-{KTB}-49 strain in the regions sequenced. {T}he complexity of these recombinant strains suggests a longstanding presence of subtype {E} in {C}entral {A}frica. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{SIDA} ; {VIRUS} ; {PHYLOGENIE} ; {ANALYSE} {GENETIQUE} ; {GENOME} ; {VIH} 1 {GROUPE} {E} ; {ZAIRE} ; {KINSHASA}}, booktitle = {}, journal = {{AIDS} {R}esearch and {H}uman {R}etroviruses}, volume = {16}, numero = {18}, pages = {2059--2064}, ISSN = {0889-2229}, year = {2000}, DOI = {10.1089/088922200750054800}, URL = {https://www.documentation.ird.fr/hor/fdi:010025682}, }