@article{fdi:010023364, title = {{H}igh heterogeneity in the number of {P}lasmodium falciparum gametocytes in the bloodmeal of mosquitoes fed on the same host}, author = {{P}ichon, {G}aston and {A}wono-{A}mbene, {H}.{P}. and {R}obert, {V}incent}, editor = {}, language = {{ENG}}, abstract = {{T}o investigate the quantitative distribution of #{P}lasmodium falciparum$ gametocytes into the vector bloodmeal, #{A}nopheles arabiensis$ mosquitoes were fed on 3 volunteers naturally infected with gametocytes. {T}he content of each mosquito midgut was smeared on a microscope slide and {G}iemsa stained. {T}he distribution of gametocytes ingested by mosquitoes followed a negative binomial distribution, with apparently constant overdispersion (parameter k plus or minus {S}.{E} = 3.105 plus or minus 0.392) for the 3 series. {T}his aggregation of gametocytes in some midguts probably facilitates the conjunction of gametes and fertilization. {T}his suggests that #{P}. falciparum$ gametocytes in the peripheral blood flow of infected man do not follow an independent, homogeneous pattern but show a significant aggregation. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{PALUDISME} ; {TRANSMISSION} ; {VECTEUR} ; {MOUSTIQUE} ; {ABSORPTION} ; {AGENT} {PATHOGENE} ; {DISTRIBUTION} {QUANTITATIVE} ; {MICROSCOPIE} {OPTIQUE} ; {GAMETOCYTE} ; {REPAS} {DE} {SANG} ; {HALOFANTRINE} ; {CHLOROQUINE} ; {DAKAR}}, booktitle = {}, journal = {{P}arasitology}, volume = {121}, numero = {}, pages = {115--120}, ISSN = {0031-1820}, year = {2000}, DOI = {10.1017/{S}0031182099006277}, URL = {https://www.documentation.ird.fr/hor/fdi:010023364}, }