@article{fdi:010021757,
  title = {{T}reatment of snake envenomations by a new polyvalent antivenom composed of highly purified {F}(ab')2 : results of a clinical trial in northern {C}ameroon},
  author = {{C}hippaux, {J}ean-{P}hilippe and {L}ang, {J}. and {A}madi-{E}ddine, {S}. and {F}agot, {P}. and {L}e {M}ener, {V}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A} clinical trail was conducted in 2 health centers in northern {C}ameroon to assess the safety and efficacy of a new polyvalent antivenom composed of higly purified and pasteurized {F}(ab')2 ({FAV}-{A}frica). {F}orty-six patients with objective signs of envenomation, including 67% with hemorrhage, were included in the study. {E}ach patient received at least 20 ml of {FAV}-{A}frica by direct, slow intravenous injection ; 172 10-ml ampules were administered. {A}ll patients were clinically cured after treatment. {T}wo patients (4.3%) showed minor immediate adverse events that may have been related to {FAV}-{A}frica (induration, light-headedness) ; no other treatment-related adverse event occurred. {N}o patient had serum sickness. {T}his trial confirms the safety of {FAV}-{A}frica administered by intravenous injection and its efficacy in the treatment of snake envenomations in sub-{S}ahara {A}frica. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{SERPENT} ; {MORSURE} ; {VENIN} ; {TRAITEMENT} {MEDICAL} ; {ANTICORPS} ; {ENFANT} ; {ADULTE} ; {ESSAI} {CLINIQUE} ; {FAV}-{AFRICA} ; {EFFET} {INDESIRABLE} ; {AFRIQUE} {SUBSAHARIENNE} ; {CAMEROUN}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {61},
  numero = {6},
  pages = {1017--1018},
  ISSN = {0002-9637},
  year = {1999},
  URL = {https://www.documentation.ird.fr/hor/fdi:010021757},
}