@incollection{fdi:010018362, title = {{A}rboviruses pathogenic for man in {B}razil}, author = {{V}asconcelos, {P}.{F}.{C}. and {T}ravassos da {R}osa, {A}.{P}.{A}. and {P}inheiro, {F}.{P}. and {S}hope, {R}.{E}. and {T}ravassos da {R}osa, {J}.{F}.{S}. and {R}odrigues, {S}.{G}. and {D}{\'e}gallier, {N}icolas and {T}ravassos da {R}osa, {E}.{S}.}, editor = {}, language = {{ENG}}, abstract = {{T}he main aspects of the clinical manifestations and epidemiological data regarding human arboviruses in the {B}razilian {A}mazon region are reviewed. {T}hirty-six arboviruses and other viruses of vertebrates have been associated with human disease among over 200 isolates made in {B}razil. {F}ive of them are important in public health and are involved in epidemics, they are the {D}engue ({DEN}), {M}ayaro ({MAY}), {O}ropouche ({ORO}), {R}ocio ({ROC}) and {Y}ellow {F}ever ({YF}) viruses. {ORO} and {DEN} are associated with epidemics of human disease in urban areas, while {MAY}, {ROC} and {YF} have been responsible for epidemics in rural areas. {U}sually, {ORO} causes a febrile disease, sometimes accompanied by aseptic meningitis. {MAY} and {DEN} are associated with febrile disease and rash, while {YF} produces a hemorrhagic fever and {ROC} is an agent responsible for encephalitis. {T}hirty-one other arboviruses are involved in rare and sporadic cases of febrile illness. {A}ll arboviruses (with the exception of {DEN} and arenaviruses) are maintained by a slyvatic cycle in the forest, where several species of hematophagous insects act as vectors and wild vertebrates are involved as hosts. {DEN} has a cycle in which the #{A}edes aegypti$ mosquitoes are the vectors and man the vertebrate host. {A}renaviruses are transmitted directly to man by rodents. {W}ith the exception of the five viruses associated with epidemics which are of great economical and social impact, and may be responsible for deaths, (e.g. of {DEN},; {ROC} and {YF}), the exact involvement of these viruses as systematic agents of human disease is unknown. {F}urther studies are needed to clarify aspects of their epidemiology. {A}renaviruses are directly transmitted to man by way of the excreta of infected rodents which are the reservoir-hosts of these viruses. {A}ppropriate safety measures should be adopted when handling these viruses as they can be transmitted via the respiratory tract (droplet infection). ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{VIRUS} ; {ARBOVIROSE} ; {EPIDEMIOLOGIE} ; {SYMPTOME} ; {TRANSMISSION} ; {VECTEUR} ; {HOTE} {VERTEBRE} ; {HOMME} ; {MILIEU} {URBAIN} ; {FORET} ; {PREVENTION} {SANITAIRE} ; {METHODE} {DE} {LUTTE} ; {ENCEPHALITE} ; {FIEVRE} {JAUNE} ; {CYCLE} {DE} {DEVELOPPEMENT} ; {BRESIL} ; {AMAZONIE}}, booktitle = {{A}n overview of arbovirology in {B}razil and neighbouring countries}, numero = {}, pages = {72--99}, address = {{B}elem}, publisher = {{I}nstituto {E}vandro {C}hagas}, series = {}, year = {1998}, ISBN = {85-86784-01-{X}}, URL = {https://www.documentation.ird.fr/hor/fdi:010018362}, }