%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture non répertoriées par l'AERES
%A Chandre, Fabrice
%A Darriet, Frédéric
%A Manguin, Sylvie
%A Brengues, Cécile
%A Carnevale, Pierre
%A Guillet, Pierre
%T Pyrethroid cross resistance spectrum among populations of Anopheles gambiae s.s. from Côte d'Ivoire
%D 1999
%L fdi:010018255
%G ENG
%J Journal of the American Mosquito Control Association
%@ 8756-971X
%K SENSIBILITE RESISTANCE ; MOUSTIQUE ; VECTEUR ; INSECTICIDE CHIMIQUE ; TEST ; MOUSTIQUAIRE IMPREGNEE ; MECANISME DE RESISTANCE ; GENE ; MUTATION ; ETUDE EXPERIMENTALE
%K PYRETHRINOIDE ; DDT ; GENE KDR
%K COTE D'IVOIRE
%N 1
%P 53-59
%U https://www.documentation.ird.fr/hor/fdi:010018255
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_49-50/010018255.pdf
%V 15
%W Horizon (IRD)
%X Field samples of #Anopheles gambiae$ s.s. from Côte d'Ivoire were tested with 5 pyrethroids (cyfluthrin, lambda-cyhalothrin, alpha-cypermethrin, deltamethrin, permethrin), 1 pseudo-pyrethroid (etofenprox), and an organochlorine (DDT). With the use of World Health Organization diagnostic tests, 5 out of 6 samples were found cross-resistant to these insecticides. A strong decrease in knockdown effect and mortality was also observed when testing deltamethrin-impregnated nettings. With a polymerase chain reaction amplification of specfic alleles diagnostic test, resistance was found associated with the presence of a kdr mutation. The strong correlation between kdr allelic frequency and resistance to DDT or etofenprox indicated that kdr was the main resistance factor for these 2 insecticides. On the contrary, a lower correlation was observed between kdr frequency and resistance to 4 of the 5 pyrethroids tested, suggesting that another mechanism was also involved, likely a metabolic detoxification. These results point out the necessity to monitor pyrethroid resistance and the presence of kdr before implementation of any impregnated bed-net programs for malaria control. (Résumé d'auteur)
%$ 052LUTIN03