@article{fdi:010018255, title = {{P}yrethroid cross resistance spectrum among populations of {A}nopheles gambiae s.s. from {C}{\^o}te d'{I}voire}, author = {{C}handre, {F}abrice and {D}arriet, {F}r{\'e}d{\'e}ric and {M}anguin, {S}ylvie and {B}rengues, {C}{\'e}cile and {C}arnevale, {P}ierre and {G}uillet, {P}ierre}, editor = {}, language = {{ENG}}, abstract = {{F}ield samples of #{A}nopheles gambiae$ s.s. from {C}{\^o}te d'{I}voire were tested with 5 pyrethroids (cyfluthrin, lambda-cyhalothrin, alpha-cypermethrin, deltamethrin, permethrin), 1 pseudo-pyrethroid (etofenprox), and an organochlorine ({DDT}). {W}ith the use of {W}orld {H}ealth {O}rganization diagnostic tests, 5 out of 6 samples were found cross-resistant to these insecticides. {A} strong decrease in knockdown effect and mortality was also observed when testing deltamethrin-impregnated nettings. {W}ith a polymerase chain reaction amplification of specfic alleles diagnostic test, resistance was found associated with the presence of a kdr mutation. {T}he strong correlation between kdr allelic frequency and resistance to {DDT} or etofenprox indicated that kdr was the main resistance factor for these 2 insecticides. {O}n the contrary, a lower correlation was observed between kdr frequency and resistance to 4 of the 5 pyrethroids tested, suggesting that another mechanism was also involved, likely a metabolic detoxification. {T}hese results point out the necessity to monitor pyrethroid resistance and the presence of kdr before implementation of any impregnated bed-net programs for malaria control. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{SENSIBILITE} {RESISTANCE} ; {MOUSTIQUE} ; {VECTEUR} ; {INSECTICIDE} {CHIMIQUE} ; {TEST} ; {MOUSTIQUAIRE} {IMPREGNEE} ; {MECANISME} {DE} {RESISTANCE} ; {GENE} ; {MUTATION} ; {ETUDE} {EXPERIMENTALE} ; {PYRETHRINOIDE} ; {DDT} ; {GENE} {KDR} ; {COTE} {D}'{IVOIRE}}, booktitle = {}, journal = {{J}ournal of the {A}merican {M}osquito {C}ontrol {A}ssociation}, volume = {15}, numero = {1}, pages = {53--59}, ISSN = {8756-971{X}}, year = {1999}, URL = {https://www.documentation.ird.fr/hor/fdi:010018255}, }