@article{fdi:010018153,
  title = {{A} cocktail of recombinant {O}nchocerca volvulus antigens for serologic diagnosis with the potential to predict the endemicity of onchocerciasis infection},
  author = {{B}radley, {J}.{E}. and {A}togho, {B}.{M}. and {E}lson, {L}. and {S}tewart, {G}.{R}. and {B}oussinesq, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e report here the evaluation of the potential of a serologic test to determine the endemicity of onchocercal infection in hyper, meso, and hypoendemic communities by the detection of antibodies to a cocktail of recombinant antigens. {P}arasitologic parameters of infection prevalence and intensity were compared with serologic results. {I}nfection prevalence by serology was consistently but not significantly higher than that defined by parasitology. {D}ifferences between the communities defined by microfilarial load ({CMFL}) and a measurement of #{O}nchocerca volvulus$-specific antibody levels (serologic index ({SI})) were similar. {W}hen stratified by age, differences were more significant in the younger age groups. {I}f a sentinel population of 5-15-year-old individuals was used to compare communities, all could be equally ranked by serologic and parasitologic parameters. {T}he {SI} of the sentinel population gave a better distinction between each community than the {SI} of the whole and would be sufficiently sensitive to measure the changes in endemicity that would be required for onchocerciasis control programs. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{ONCHOCERCOSE} ; {ENDEMIE} ; {DIAGNOSTIC} ; {SEROLOGIE} ; {ANTIGENE} ; {TEST} {ELISA} ; {PREVALENCE} ; {ANTIGENE} {RECOMBINE}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {59},
  numero = {6},
  pages = {877--882},
  ISSN = {0002-9637},
  year = {1998},
  URL = {https://www.documentation.ird.fr/hor/fdi:010018153},
}