@article{fdi:010015517, title = {{D}emographic, ethnic, and geographic differences between {H}uman {T} cell {L}ymphotropic {V}irus ({HTLV}) type {I}-seropositive carriers and persons with {HTLV}-1 gag indeterminate western blots in {C}entral {A}frica}, author = {{M}aucl{\`e}re, {P}. and {L}e {H}esran, {J}ean-{Y}ves and {M}ahieux, {R}. and {S}alla, {R}. and {M}foupouendoun, {J}. and {A}bada, {E}.{T}. and {M}illan, {J}. and {T}h{\'e}, {G}. {D}e and {G}essain, {A}.}, editor = {}, language = {{ENG}}, abstract = {{U}sing stringent {W}estern blot ({WB}) criteria, human {T} cell lymphotropic virus ({HTLV}) type {I} seroprevalence among 3783 persons from representative rural populations of {C}ameroon averaged 1.1% and was higher in females (1.5%) and in {P}ygmies (2.0%), increasing with age. {F}urthermore, an {HTLV}-{I} {G}ag-indeterminate {WB} profile ({HGIP}), exhibiting strong reactivities to p19, p26, p28, p32, p36, and pr 53 but lacking both p24 and env reactivity, was observed in 1.6% of the same populations. {T}he prevalence of the {HGIP} was similar between males and females, did not increase with age, and appeared to cluster in tropical forests of {S}outhern {C}ameroon, especially among {P}ygmies (reaching 4%). {T}hese contrasting epidemiologic features, together with the lack of detection by polymerase chain reaction of {HTLV}-{I} sequences in the peripheral blood mononuclear cells of the persons with {HGIP}, strongly suggest that such a {WB} profile does not appear to reflect an {HTLV}-{I} related viral infection but possibly an environmental (viral or parasitic) factor endemic in tropical rain forest areas. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{VIRUS} ; {EPIDEMIOLOGIE} ; {SEROLOGIE} ; {PREVALENCE} ; {SEX} {RATIO} ; {ETHNIE} ; {HTLV}-1 ; {CAMEROUN} {SUD}}, booktitle = {}, journal = {{T}he {J}ournal of {I}nfectious {D}iseases}, volume = {176}, numero = {}, pages = {505--509}, ISSN = {0022-1899}, year = {1997}, DOI = {10.1086/514071}, URL = {https://www.documentation.ird.fr/hor/fdi:010015517}, }