@article{fdi:010014424,
  title = {{C}omplete nucleotide sequence of an {A}frican human {T}-lymphotropic virus type {II} subtype b isolate ({HTLV}-{II}-{G}ab) : molecular and phylogenetic analysis},
  author = {{L}etourneur, {F}. and {A}uriol, {L}. d' and {D}azza, {M}.{C}. and {P}eeters, {M}artine and {B}edjabaga, {I}. and {P}iot, {P}. and {D}elaporte, {E}ric and {G}essain, {A}. and {M}onplaisir, {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e report the first complete nucleotide sequence of an african human {T}-cell lymphotropic virus type {II}. {T}his new strain, called {HTLV}-{II}-{G}ab ({G}ab), was obtained from the uncultured peripheral blood mononuclear cells of a 44-year-old healthy gabonese male who lived in a remote rural area, with neither history of blood transfusion nor sexual intercourse with non-africans. {U}sing nested {PCR}, 25 overlapping fragments, representing the entire proviral genome, were obtained, cloned and sequenced. {T}he overall nucleotide sequence comparison with the four other available complete {HTLV}-{II} genomes indicated that {G}ab was more closely related to the {HTLV}-{II} subtype b prototypes (98.9, 99.3 and 98.2 % nucleotide similarity with {G}12, {NRA} and {GU} respectively) than to the subtype a prototype (95.1 % nucleotide similarity with {M}o). {R}estriction profiles studies and phylogenetic analyses confirmed that {G}ab was a subtype b strain. {H}owever, this strain represents a newly described restriction fragment length polymorphism subtype, closely related to one of the rare partially sequenced {A}frican isolates originating from a pygmy living in {C}ameroon ({PYGCAM}). {N}evertheless, the very low genetic divergence observed between this new african strain and the american strains raises several questions on the origins and level of genetic variability over time of this human retrovirus. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{VIRUS} ; {GENOME} ; {VARIABILITE} {GENETIQUE} ; {TECHNIQUE} {PCR} ; {PHYLOGENIE} ; {HTLV}-2-{GAB}},
  booktitle = {},
  journal = {{J}ournal of {G}eneral {V}irology},
  volume = {79},
  numero = {},
  pages = {269--277},
  ISSN = {0001-5060},
  year = {1998},
  URL = {https://www.documentation.ird.fr/hor/fdi:010014424},
}