@article{fdi:010013980,
  title = {{A} phylogenetic analysis of the {T}rypanosoma cruzi genome project {CL} {B}rener reference strain by multilocus enzyme electrophoresis and multiprimer random amplified polymorphic {DNA} fingerprinting},
  author = {{B}risse, {S}ylvain and {B}arnab{\'e}, {C}hristian and {B}anuls, {A}nne-{L}aure and {S}idib{\'e}, {I}. and {N}o{\¨e}l, {S}. and {T}ibayrenc, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e have assessed the phylogenetic status of the #{T}rypanosoma cruzi$ {G}enome {P}roject {CL} {B}rener reference strain by multilocus enzyme electrophoresis ({MLEE}) and multiprimer random amplified polymorphic {DNA} ({RAPD}) including a set of cloned stocks representative of the whole genetic diversity of #{T}. cruzi$. {MLEE} and {RAPD} data gave congruent phylogenetic results. {T}he {CL} {B}rener reference strain fell into the second major phylogenetic subdivision of #{T}. cruzi$, and was genetically very close to the {T}ulahuen reference strain. {N}o reliable {RAPD} character and only one {MLEE} character permitted us to distinguish between the {CL} {B}rener and {T}ulahuen reference strain. {I}n contrast, many {RAPD} and {MLEE} characters were able to distinguish between the {CL} {B}rener reference strain and the other #{T}. cruzi$ genotypes analyzed here, in particular the formerly described principal zymodemes {I}, {II} and {III}. {I}t is suspected that both {CL} {B}rener and {T}ulahuen are hybrid genotypes, a fact that should be taken into account when interpreting sequence data. {M}oreover, our study confirms that the species #{T}. cruzi$ is genetically very heterogeneous. {W}e recommend future comparison of sequencing data from the {CL} {B}rener reference strain with those of at least one radically distinct #{T}. cruzi$ genotype, belonging to the other major phylogenetic subdivision of this species. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{MALADIE} {DE} {CHAGAS} ; {AGENT} {PATHOGENE} ; {CLONE} ; {GENOTYPE} ; {PHYLOGENIE} ; {ELECTROPHORESE} ; {TECHNIQUE} {RAPD} ; {CARACTERISATION} {GENETIQUE}},
  booktitle = {},
  journal = {{M}olecular and {B}iochemical {P}arasitology},
  volume = {92},
  numero = {2},
  pages = {253--263},
  ISSN = {0166-6851},
  year = {1998},
  DOI = {10.1016/{S}0166-6851(98)00005-{X}},
  URL = {https://www.documentation.ird.fr/hor/fdi:010013980},
}