@article{fdi:010013501,
  title = {{G}enetic subtypes of {HIV} type 1 and {HIV} type 2 strains in commercial sex workers from {B}amako, {M}ali},
  author = {{P}eeters, {M}artine and {K}oumar{\'e}, {B}. and {M}ulanga, {C}laire and {B}rengues, {C}{\'e}cile and {M}ounirou, {B}. and {B}ougoudogo, {F}. and {R}avel, {S}ophie and {B}ibollet-{R}uche, {F}r{\'e}d{\'e}ric and {D}elaporte, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n {A}frica the highest {HIV} infection rate has been reported among female commercial sex workers ({CSW}s) who are at increasing risk of acquiring and transmitting {HIV} infection. {I}n {O}ctober 1995, 176 {CSW}s were studied in {B}amako, the capital city of {M}ali. {T}he ages of the {CSW}s ranged from 15 to 50 years old (mean, 28.8 years). {O}nly 20.45% of the 176 {CSW}s were {M}alian ; the majority were from {N}igeria (32.9%) and {G}hana (31.8%), and the remaining were from other {A}frican countries. {F}orty-one percent were active for less than 1 year as a commercial sex worker, and the length of prostitution for the remaining women ranged from 1 to 15 years (mean, 2.76). {A} total of 81 (46.02%) of the 176 {CSW}s were positive for {HIV} antibodies ; 63 (35.8%) were {HIV}-1 positive, 3.9% were {HIV}-2 posivitive, 11 (6.2%) had antibodies to {HIV}-1 and {HIV}-2, and none of them had antibodies to group {O} viruses. {F}or all {HIV} antibody-positive samples, {PBMC}s were separated and genetic subtypes of {HIV}-1 were determined using the heteroduplex mobility assay ({HMA}), with {ED}5-{ED}12 as outer and {ES}7-{ES}8 as inner primers. {A}mong the 66 {HIV}-1 strains characterized, 53 (80.3%) were subtype {A}, 2 (3.1%) belonged to subtype {C}, 1 (1.5%) belonged to subtype {D}, and 10 (15.1%) were identified as subtype {G}. {A}mong the 10 subtype {G} strains, 8 were obtained from women who were very recent {CSW}s, with an activity of 1 year or less, assuming that there is a high probability that these infections occurred recently. {G}enetic subtypes of five {HIV}-2 viruses were determined by sequencing of the env and/or gag genes followed by phylogenetic analysis, and all of them belonged to subtype {A}. {C}omparison of {HIV}-1 and {HIV}-2 seroprevalence data from our study with previous data from {M}ali shows a significant rise in {HIV}-1 prevalence and a significant decrease in {HIV}-2 prevalence and confirms similar trends observed in neighboring countries... ({D}'apr{\`e}s r{\'e}sum{\'e} d'auteur)},
  keywords = {{SIDA} ; {PROSTITUTION} ; {VIRUS} ; {VARIABILITE} {GENETIQUE} ; {ANALYSE} ; {VIH}-1 ; {VIH}-2 ; {SEROPREVALENCE} ; {MALI} ; {BAMAKO}},
  booktitle = {},
  journal = {{AIDS} {R}esearch and {H}uman {R}etroviruses},
  volume = {14},
  numero = {1},
  pages = {51--58},
  ISSN = {0889-2229},
  year = {1998},
  DOI = {10.1089/aid.1998.14.51},
  URL = {https://www.documentation.ird.fr/hor/fdi:010013501},
}