Cot Michel auteur aut IRD Le Hesran Jean-Yves auteur aut IRD Miailhes P. auteur aut IRD Roisin A. auteur aut IRD Fievet Nadine auteur aut IRD Barro D. auteur aut IRD Etya'ale D. auteur aut IRD Deloron Philippe auteur aut IRD Carnevale Pierre auteur aut IRD Bréart G. auteur aut IRD text journalArticle eng text/pdf reformatted digital access Two controlled trials of chloroquine prophylaxis during pregnancy were performed, one in Burkina Faso in 1987, on all pregnant women, and the other in Cameroon in 1992, on primigravidae only. Maternal haematocrit at delivery was found to be significantly higher in those women who had received chloroquine than in those who had not, both in Burkina Faso (37.4% v. 36.5% ; P=0.01) and in Cameroon (34.8% v. 32.8% ; P=0.02). Anaemia, defined as an haematocrit of < 30%, was also less common in those treated with chloroquine (6.3% v. 8.5% in Burkina Faso and 8.3% v. 18.4% in Cameroon) but this difference was not significant in either country. A slight improvement in haematological status when prophylaxis is given has also been observed in similar studies performed in other tropical countries. The present results confirm the usefulness of targeting antimalarial prophylaxis at pregnant women. Such prophylaxis during the first pregnancy also increases birthweight. (Résumé d'auteur) specialized PALUDISME GROSSESSE PREVENTION SANITAIRE ANEMIE POIDS DE NAISSANCE CHLOROQUINE HEMATOCRITE MATERNEL PRIMIGESTE PALUDISME PLACENTAIRE CAMEROUN BURKINA FASO 052ANOPAL04 92 1 37-43 1998 0003-4983 https://www.documentation.ird.fr/hor/fdi:010012616 10.1080/00034989860157 0003-4983 [F B010012616] https://www.documentation.ird.fr/hor/fdi:010012616 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_47-48/010012616.pdf IRD - Base Horizon / Pleins textes 1998-02-02 2017-08-07 fdi:010012616 fre