@article{fdi:010012616, title = {{E}ffect of chloroquine prophylaxis during pregnancy on maternal haematocrit}, author = {{C}ot, {M}ichel and {L}e {H}esran, {J}ean-{Y}ves and {M}iailhes, {P}. and {R}oisin, {A}. and {F}ievet, {N}adine and {B}arro, {D}. and {E}tya'ale, {D}. and {D}eloron, {P}hilippe and {C}arnevale, {P}ierre and {B}r{\'e}art, {G}.}, editor = {}, language = {{ENG}}, abstract = {{T}wo controlled trials of chloroquine prophylaxis during pregnancy were performed, one in {B}urkina {F}aso in 1987, on all pregnant women, and the other in {C}ameroon in 1992, on primigravidae only. {M}aternal haematocrit at delivery was found to be significantly higher in those women who had received chloroquine than in those who had not, both in {B}urkina {F}aso (37.4% v. 36.5% ; {P}=0.01) and in {C}ameroon (34.8% v. 32.8% ; {P}=0.02). {A}naemia, defined as an haematocrit of < 30%, was also less common in those treated with chloroquine (6.3% v. 8.5% in {B}urkina {F}aso and 8.3% v. 18.4% in {C}ameroon) but this difference was not significant in either country. {A} slight improvement in haematological status when prophylaxis is given has also been observed in similar studies performed in other tropical countries. {T}he present results confirm the usefulness of targeting antimalarial prophylaxis at pregnant women. {S}uch prophylaxis during the first pregnancy also increases birthweight. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{PALUDISME} ; {GROSSESSE} ; {PREVENTION} {SANITAIRE} ; {ANEMIE} ; {POIDS} {DE} {NAISSANCE} ; {CHLOROQUINE} ; {HEMATOCRITE} {MATERNEL} ; {PRIMIGESTE} ; {PALUDISME} {PLACENTAIRE} ; {CAMEROUN} ; {BURKINA} {FASO}}, booktitle = {}, journal = {{A}nnals of {T}ropical {M}edicine and {P}arasitology}, volume = {92}, numero = {1}, pages = {37--43}, ISSN = {0003-4983}, year = {1998}, DOI = {10.1080/00034989860157}, URL = {https://www.documentation.ird.fr/hor/fdi:010012616}, }