%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture non répertoriées par l'AERES
%A Penchenier, Laurent
%A Mathieu-Daudé, F.
%A Brengues, Cécile
%A Banuls, Anne-Laure
%A Tibayrenc, Michel
%T Population structure of Trypanosoma brucei S.L. in Cote d'Ivoire assayed by multilocus enzyme electrophoresis : epidemiological and taxonomical considerations
%D 1997
%L fdi:010011086
%G ENG
%J Journal of Parasitology
%@ 0022-3395
%K MALADIE DU SOMMEIL ; AGENT PATHOGENE ; GENETIQUE DE POPULATION ; SPECIATION ; GENOTYPE
%K ELECTROPHORESE ENZYMATIQUE
%K COTE D'IVOIRE
%N 1
%P 19-22
%U https://www.documentation.ird.fr/hor/fdi:010011086
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_47-48/010011086.pdf
%V 83
%W Horizon (IRD)
%X Fifty-two #Trypanosoma brucei$ stocks isolated in Côte d'Ivoire from sympatric locations were analyzed by cellulose acetate electrophoresis of isoenzymes. Of 13 genetic loci surveyed, 5 appeared as variable, which made it possible to delimit 12 different zymodemes. The most abundant zymodeme involved stocks isolated from both humans and pigs, which is consistent with the hypothesis that pig is a reservoir of human African trypanosomiasis in Côte d'Ivoire, as already proposed by other authors. Population genetic analysis of the isozyme data indicated a strong linkage disequilibrium, which suggests that genetic recombination is severely restricted in this sample and favors the hypothesis that the trypanosome populations surveyed are basically clonal. Nevertheless, additional studies are required to better estimate the long-term stability of these clones and the possible interference of gene exchange at an evolutionary scale. The results corroborate the hypothesis that a majority of human #T. brucei$ stocks from West Africa correspond to a fairly homogeneous cluster of genotypes. (Résumé d'auteur)
%$ 052GLOTRY02