@inproceedings{fdi:010008217,
  title = {{I}mmunostimulating effect of zinc supplement during recovery of severe malnourished children},
  author = {{C}hevalier, {P}hilippe and {S}evilla, {R}. and {Z}alles, {L}. and {B}elmonte, {G}. and {S}ejas, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{R}ecovery of normal anthropometric values was observed after one month of rehabilitation in young children suffering from severe protein-energy malnutrition. {B}ut one another month was required for immunologic recovery and the children were kept in the rehabilitation ward until nutritional and immunological recovery. {T}o accelerate the immune rehabilitation of the children we investigated the effect of a daily zinc supplementation (2 mg per kg) as an immuno-stimulatory treatment. {T}he percentage of immature lymphocytes and non-invasive ultrasonography of the thymic mass were used to estimate the immune rehabilitation. {B}ecause the hospital ethical committee refused a comparative study with placebo, a case-historically matched cohort study of 32 malnourished children was planed. {C}hildren of both groups underwent nutritional rehabilitation for two months. {I}n addition, the test group received a daily zinc supplementation. {I}n both groups anthropometric recovery was achieved in one month. {C}hildren with daily zinc supplementation showed faster thymic mass recovery than controls and reached immune recovery in one month while an another month was needed for controls. {Z}inc supplementation did not hasten anthropometrical recovery but significantly reduced the time for immunological recovery. {Z}inc supplementation acted as an immune-stimulating factor so that immune and anthropometric recoveries coincided. {Z}inc supplement allowed the discharge of "anthropometrically and immunologically healthy" children after only one month of treatment. {H}ospitalization time could be shortened and the cost reduced by half. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{MALNUTRITION} {PROTEINOENERGETIQUE} ; {REHABILITATION} {NUTRITIONNELLE} ; {SUPPLEMENTATION} ; {ZINC} ; {IMMUNITE} ; {ENFANT} ; {ANTHROPOMETRIE} {NUTRITIONNELLE}},
  volume = {9},
  numero = {4},
  pages = {239},
  booktitle = {{T}race elements in medicine and biology : therapeutic uses of trace elements},
  year = {1995},
  ISSN = {0896-548{X}},
  URL = {https://www.documentation.ird.fr/hor/fdi:010008217},
}