@article{fdi:010007536,
  title = {{S}hort report : gametocytes, chloroquine pressure, and the relative parasite survival advantage of resistant strains of {F}alciparum malaria in {W}est {A}frica},
  author = {{R}obert, {V}incent and {M}olez, {J}ean-{F}ran{\c{c}}ois and {T}rape, {J}ean-{F}ran{\c{c}}ois},
  editor = {},
  language = {{ENG}},
  abstract = {{P}atients with #{P}lasmodium falciparum$ infections were selected with an in vivo chloroquine sensitivity assay. {F}ourteen days after treatment, the gametocytes were studied in relation to asexual parasite responses classified as drug-sensitive or showing {RI} or {RII} resistance. {G}ametocyte prevalence and density appeared significantly higher in {RII} than {RI} strains and higher in {RI} than in sensitive strains. {T}his finding on gametocyte variation in vivo may explain why the {RII} type of chloroquine resistance has became more prevalent than {RI} everywhere in tropical {A}frica in the short time since its emergence. {T}he biological and epidemiologic advantage of chloroquine-resistant malaria mediated through gametocytes is discussed in the context of the present drug pressure in {A}frica. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{PALUDISME} ; {AGENT} {PATHOGENE} ; {SENSIBILITE} {RESISTANCE} ; {EPIDEMIOLOGIE} ; {PREVALENCE} ; {EFFICACITE} ; {TRAITEMENT} {MEDICAL} ; {CHLOROQUINE} ; {AFRIQUE} {DE} {L}'{OUEST} ; {SENEGAL} ; {DAKAR}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {55},
  numero = {3},
  pages = {350--351},
  ISSN = {0002-9637},
  year = {1996},
  URL = {https://www.documentation.ird.fr/hor/fdi:010007536},
}