@article{PAR00022977,
  title = {{A} cluster of {A}nkyrin and {A}nkyrin-{TPR} repeat genes is associated with panicle branching diversity in rice},
  author = {{K}hong, {G}. {N}. and {L}e, {N}. {T}. and {P}ham, {M}. {T}. and {A}dam, {H}{\'e}l{\`e}ne and {G}auron, {C}arole and {L}e, {H}. {Q}. and {P}ham, {D}. {T}. and {C}olonges, {K}. and {P}ham, {X}. {H}. and {D}o, {V}. {N}. and {L}ebrun, {M}. and {J}ouannic, {S}tefan},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he number of grains per panicle is an important yield-related trait in cereals which depends in part on panicle branching complexity. {O}ne component of this complexity is the number of secondary branches per panicle. {P}reviously, a {GWAS} site associated with secondary branch and spikelet numbers per panicle in rice was identified. {H}ere we combined gene capture, bi-parental genetic population analysis, expression profiling and transgenic approaches in order to investigate the functional significance of a cluster of 6 {ANK} and {ANK}-{TPR} genes within the {QTL}. {F}our of the {ANK} and {ANK}-{TPR} genes present a differential expression associated with panicle secondary branch number in contrasted accessions. {T}hese differential expression patterns correlate in the different alleles of these genes with specific deletions of potential cis-regulatory sequences in their promoters. {T}wo of these genes were confirmed through functional analysis as playing a role in the control of panicle architecture. {O}ur findings indicate that secondary branching diversity in the rice panicle is governed in part by differentially expressed genes within this cluster encoding {ANK} and {ANK}-{TPR} domain proteins that may act as positive or negative regulators of panicle meristem's identity transition from indeterminate to determinate state. {A}uthor summary {G}rain yield is one of the most important indexes in rice breeding, which is controlled in part by panicle branching complexity. {A} new {QTL} with co-location of spikelet number ({S}p{N}) and secondary branch number ({SBN}) traits was identified by genome-wide association study in a {V}ietnamese rice landrace panel. {A} set of four {A}nkyrin and {T}etratricopeptide repeat domain-encoding genes was identified from this {QTL} based on their difference of expression levels between two contrasted haplotypes for the {S}p{N} and {SBN} traits. {T}he differential expression is correlated with deletions in the promoter regions of these genes. {T}wo of the genes act as negative regulators of the panicle meristem's identity transition from indeterminate to determinate state while the other two act as positive regulators of this meristem fate transition. {B}ased on the different phenotypes between overexpressed and mutant plants, two of these genes were confirmed as playing a role in the control of panicle architecture. {T}hese findings can be directly used to assist selection for grain yield improvement.},
  keywords = {},
  booktitle = {},
  journal = {{PL}o{S} {G}enetics},
  volume = {17},
  numero = {6},
  pages = {e1009594 [24 p.]},
  ISSN = {1553-7404},
  year = {2021},
  DOI = {10.1371/journal.pgen.1009594},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00022977},
}