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    <abstract>Background. Although men who have sex with men (MSM) are at high risk of hepatitis B virus (HBV) infection, they do not have access to vaccination in West Africa, which is a highly endemic region. We investigated HBV prevalence and associated factors, as well as acceptability and difficulties of vaccination in MSM enrolled in an operational research program in Burkina Faso, Cote d'Ivoire, Mali, and Togo. Methods. We followed up 779 MSM in 2015-2018. Participants who were negative for both hepatitis B surface antigen (HBsAg) and antibodies (anti-HBs) at enrollment were offered HBV vaccination. Factors associated with HBV infection were identified using logistic regression models. Results. Overall, HBV prevalence was 11.2% (95% confidence interval [CI], 9.0%-13.6%). It was lower in Togo than in Cote d'Ivoire (2.7% vs 17.3%; adjusted odds ratio [aOR], 0.12; 95% CI, 0.02-0.28) and higher in participants with 6+ recent male sexual partners (21.0% vs 9.3%; aOR, 1.48; 95% CI, 1.12-1.97). Of 528 participants eligible for vaccination, 484 (91.7%) were willing to be vaccinated and received at least 1 dose (ranging from 68.2% in Abidjan to 96.4% in Bamako; P &lt; .001). Of the latter, 390 (80.6%) received 3 or 4 doses. The proportion of participants for whom the minimum required time between each dose was respected ranged from 10.9% in Bamako to 88.6% in Lome (P &lt; .001). Conclusions. MSM in West Africa should be targeted more for HBV screening and vaccination. Although vaccination is well accepted by MSM, greater training of health care workers and education of MSM are required.</abstract>
    <targetAudience authority="marctarget">specialized</targetAudience>
    <subject>
      <topic>Africa</topic>
      <topic>hepatitis B</topic>
      <topic>men who have sex with men</topic>
      <topic>prevalence</topic>
      <topic>vaccination</topic>
    </subject>
    <subject authority="local">
      <geographic>BAMAKO</geographic>
      <geographic>MALI</geographic>
      <geographic>ABIDJAN</geographic>
      <geographic>COTE D’IVOIRE</geographic>
      <geographic>OUAGADOUGOU</geographic>
      <geographic>BURKINA FASO</geographic>
      <geographic>LOME</geographic>
      <geographic>TOGO</geographic>
    </subject>
    <classification authority="local">052</classification>
    <classification authority="local">056</classification>
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      <titleInfo>
        <title>Open Forum Infectious Diseases</title>
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      <part>
        <detail type="volume">
          <number>6</number>
        </detail>
        <detail type="volume">
          <number>7</number>
        </detail>
        <extent unit="pages">
          <list> ofz249 [9 p.]</list>
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      <originInfo>
        <dateIssued>2019</dateIssued>
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      <identifier type="issn">2328-8957</identifier>
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    <identifier type="uri">https://www.documentation.ird.fr/hor/PAR00019846</identifier>
    <identifier type="doi">10.1093/ofid/ofz249</identifier>
    <identifier type="issn">2328-8957</identifier>
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