Horizon 1 1 17 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES Phytochemistry 262-272 Dendrobangia boliviana Cardiopteridaceae Triterpenoid saponins Cytotoxic activity PEROU AMAZONIE 2016 PAR00015090 ENG Phytochemistry 0031-9422 ISI:000383302900026 10.1016/j.phytochem.2016.06.006 https://www.documentation.ird.fr/hor/PAR00015090 https://www.documentation.ird.fr/intranet/publi/2016/10/010068140.pdf 130 Horizon (IRD) Twelve oleanane saponins, zebiriosides A-L, were isolated from the roots of Dendrobangia boliviana Rusby, together with two known saponins, talunumoside I and 3-O-beta-D-glucuronopyranosyl serjanic acid. These saponins are glycosides of serjanic or phytolaccinic acid. Their structures were established on two basis: first, their spectral data, mainly HR-TOFESIMS, 1D-NMR (H-1, C-13, DEPT) and 2D-NMR (H-1-H-1 COSY, TOCSY, HSQC, HMBC, and ROESY), and second by comparison with literature data. These compounds were evaluated for their cytotoxic, antileishmanial and hemolytic activities. No antileishmanial or hemolytic activities were revealed, however zebirioside C and zebirioside I showed cytotoxicity against fibroblasts with IC50 of 6.4 and 5.6 mu M, respectively. 076 ; 020 UR152 Pérou