@article{PAR00009901,
  title = {{N}euroendocrine control by dopamine of teleost reproduction},
  author = {{D}ufour, {S}ylvie and {S}ebert, {M}. {E}. and {W}eltzien, {F}. {A}. and {R}ousseau, {K}. and {P}asqualini, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{W}hile gonadotropin-releasing hormone ({G}n{RH}) is considered as the major hypothalamic factor controlling pituitary gonadotrophins in mammals and most other vertebrates, its stimulatory actions may be opposed by the potent inhibitory actions of dopamine ({DA}) in teleosts. {T}his dual neuroendocrine control of reproduction by {G}n{RH} and {DA} has been demonstrated in various, but not all, adult teleosts, where {DA} participates in an inhibitory role in the neuroendocrine regulation of the last steps of gametogenesis (final oocyte maturation and ovulation in females and spermiation in males). {T}his has major implications for inducing spawning in aquaculture. {I}n addition, {DA} may also play an inhibitory role during the early steps of gametogenesis in some teleost species, and thus interact with {G}n{RH} in the control of puberty. {V}arious neuroanatomical investigations have shown that {DA} neurones responsible for the inhibitory control of reproduction originate in a specific nucleus of the preoptic area ({NPO}av) and project directly to the region of the pituitary where gonadotrophic cells are located. {P}harmacological studies showed that the inhibitory effects of {DA} on pituitary gonadotrophin production are mediated by {DA}-{D}2 type receptors. {DA}-{D}2 receptors have now been sequenced in several teleosts, and the coexistence of several {DA}-{D}2 subtypes has been demonstrated in a few species. {H}ypophysiotropic {DA} activity varies with development and reproductive cycle and probably is controlled by environmental cues as well as endogenous signals. {S}ex steroids have been shown to regulate dopaminergic systems in several teleost species, affecting both {DA} synthesis and {DA}-{D}2 receptor expression. {T}his demonstrates that sex steroid feedbacks target {DA} hypophysiotropic system, as well as the other components of the brain-pituitary gonadotrophic axis, {G}n{RH} and gonadotrophins. {R}ecent studies have revealed that melatonin modulates the activity of {DA} systems in some teleosts, making the melatonin-{DA} pathway a prominent relay between environmental cues and control of reproduction. {T}he recruitment of {DA} neurons for the neuroendocrine control of reproduction provides an additional brain pathway for the integration of various internal and environmental cues. {T}he plasticity of the {DA} neuroendocrine role observed in teleosts may have contributed to their large diversity of reproductive cycles.},
  keywords = {dopamine ; dopamine-{D}2 receptors ; reproduction ; sex steroids ; teleosts},
  booktitle = {},
  journal = {{J}ournal of {F}ish {B}iology},
  volume = {76},
  numero = {1},
  pages = {129--160},
  ISSN = {0022-1112},
  year = {2010},
  DOI = {10.1111/j.1095-8649.2009.02499.x},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00009901},
}