@article{PAR00009332,
  title = {{A} seroepidemiological study of pandemic {A}/{H}1{N}1(2009) influenza in a rural population of {M}ali},
  author = {{K}oita, {O}. {A}. and {S}angare, {L}. and {P}oudiougou, {B}. and {A}boubacar, {B}. and {S}amake, {Y}. and {C}oulibaly, {T}. and {P}ronyk, {P}. and {S}alez, {N}. and {K}ieffer, {A}. and {N}inove, {L}. and {F}lahault, {A}. and {D}e {L}amballerie, {X}avier},
  editor = {},
  language = {{ENG}},
  abstract = {{C}lin {M}icrobiol {I}nfect 2012; 18: 976981 {A}bstract {T}he swine-origin {H}1{N}1 influenza {A} virus (p{H}1{N}1(2009)) started to circulate worldwide in 2009, and cases were notified in a number of sub-{S}aharan {A}frican countries. {H}owever, no epidemiological data allowing estimation of the epidemic burden were available in this region, preventing comprehensive comparisons with other parts of the world. {T}he {C}o{P}an{F}lu-{M}ali programme studied a cohort of 202 individuals living in the rural commune of {D}ioro (southern central {M}ali). {P}re-pandemic and post-pandemic paired sera (sampled in 2006 and {A}pril 2010, respectively) were tested by the haemagglutination inhibition ({HI}) method. {D}ifferent estimates of p{H}1{N}1(2009) infection during the 2009 first epidemic wave were used (increased prevalence of {HI} titre of =1/40 or =1/80, seroconversions) and provided convergent attack rate values (12.414.9%), the highest values being observed in the 019-year age group (16.018.4%). {I}n all age groups, pre-pandemic {HI} titres of =1/40 were associated with complete absence of seroconversion; and geometric mean titres were <15 in individuals who seroconverted and >20 in others. {I}mportant variations in seroconversion rate existed among the different villages investigated. {D}espite limitations resulting from the size and composition of the sample analysed, this study provides strong evidence that the impact of the p{H}1{N}1(2009) first wave was more important than previously believed, and that the determinants of the epidemic spread in sub-{S}aharan populations were quite different from those observed in developed countries.},
  keywords = {{E}pidemiology ; {H}1{N}1 ; haemagglutination inhibition ; influenza ; {M}ali ; pandemic ; sub-{S}aharan {A}frica},
  booktitle = {},
  journal = {{C}linical {M}icrobiology and {I}nfection},
  volume = {18},
  numero = {10},
  pages = {976--981},
  ISSN = {1198-743{X}},
  year = {2012},
  DOI = {10.1111/j.1469-0691.2011.03725.x},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00009332},
}