@article{PAR00009076,
  title = {{C}arbapenem resistance and {A}cinetobacter baumannii in {S}enegal : the paradigm of a common phenomenon in natural reservoirs},
  author = {{K}empf, {M}. and {R}olain, {J}. {M}. and {D}iatta, {G}. and {A}zza, {S}. and {S}amb, {B}. and {M}ediannikov, {O}leg and {S}ow, {A}. {G}. and {D}iene, {S}. {M}. and {F}enollar, {F}. and {R}aoult, {D}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}ncidence of carbapenem-resistant {A}cinetobacter baumannii is rising in several parts of the world. {I}n {A}frica, data concerning this species and its resistance to carbapenems are limited. {T}he objective of the present study was to identify the presence of {A}. baumannii carbapenem-resistant encoding genes in natural reservoirs in {S}enegal, where antibiotic pressure is believed to be low. {F}rom {O}ctober 2010 to {J}anuary 2011, 354 human head lice, 717 human fecal samples and 118 animal fecal samples were screened for the presence of {A}. baumannii by real time {PCR} targeting bla({OXA}51-like) gene. {F}or all samples positive for {A}. baumannii, the carbapenemase-hydrolysing oxacillinases bla({OXA}23-like) and bla({OXA}24-like) were searched for and sequenced, and the isolates harbouring an oxacillinase were genotyped using {PCR} amplification and sequencing of rec{A} gene. {T}he presence of {A}. baumannii was detected in 4.0% of the head lice, in 5.4% of the human stool samples and in 5.1% of the animal stool samples tested. {N}o bla({OXA}24) gene was detected but six fecal samples and three lice were positive for bla({OXA}23-like) gene. {T}he bla({OXA}23-like) gene isolated in lice was likely a new oxacillinase sequence. {F}inally, the {A}. baumannii detected in stools were all of rec{A} genotype 3 and those detected in lice, of rec{A} genotype 4. {T}his study shows for the first time a reservoir of bla({OXA}23-like)-positive gene in human head lice and stool samples in {S}enegal.},
  keywords = {},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {7},
  numero = {6},
  pages = {e39495},
  ISSN = {1932-6203},
  year = {2012},
  DOI = {10.1371/journal.pone.0039495},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00009076},
}