@article{PAR00009008, title = {{I}mpact of environmental {DDT} concentrations on gill adaptation to increased salinity in the tilapia {S}arotherodon melanotheron}, author = {{R}iou, {V}irginie and {N}diaye, {A}. and {B}udzinski, {H}. and {D}ugu{\'e}, {R}{\'e}mi and {L}e {M}enach, {K}. and {C}ombes, {Y}. and {B}ossus, {M}. and {D}urand, {J}ean-{D}ominique and {C}harmantier, {G}. and {L}orin-{N}ebel, {C}.}, editor = {}, language = {{ENG}}, abstract = {{E}stuaries of tropical developing countries suffering from severe droughts induced by climate change are habitats to fish, which face drastic salinity variations and the contact with pollutants. {T}he {W}estern {A}frica tilapia {S}arotherodon melanotheron is highly resistant to hypersalinity, but the effect of human-released xenobiotics on its adaptation is barely known. {C}ontrolled experiments were conducted to observe {S}. melanotheron gill adaptation to abrupt salinity variations in the presence of waterborne {DDT}, at concentrations detected in their natural habitat. {T}he gills appeared as an important site of {DDT} conversion to {DDD} and/or depuration. {A} 12-days {DDT} exposure resulted in decreased gill epithelium thickness at all salinities (from fresh- to hypersaline-water), and the structure of gills from freshwater fish was particularly altered, relative to controls. {N}o unbalance in tilapia blood osmolality was observed following {DDT} exposure, which however caused a decrease in branchial {N}a+-{K}+-{ATP}ase ({NKA}) activity. {G}ill cellular {NKA} expression was reduced in salt-water, together with the expression of the {CFTR} chloride channel in hypersaline water. {A}lthough {S}. melanotheron seems very resistant (especially in seawater) to short-term waterborne {DDT} contamination, the resulting alterations of the gill tissue, cells and enzymes might affect longer term respiration, toxicant depuration and/or osmoregulation in highly fluctuating salinities.}, keywords = {{DDT}s ; {F}ish ; {G}ill ; {N}a+/{K}+-{ATP}ase ; {O}smoregulation ; {T}eleost}, booktitle = {}, journal = {{C}omparative {B}iochemistry and {P}hysiology {C} : {T}oxicology and {P}harmacology}, volume = {156}, numero = {1}, pages = {7--16}, ISSN = {1532-0456}, year = {2012}, DOI = {10.1016/j.cbpc.2012.03.002}, URL = {https://www.documentation.ird.fr/hor/{PAR}00009008}, }