@article{PAR00008873,
  title = {{A}ntiproliferative activity against human non-small cell lung cancer of two {O}-alkyl-diglycosylglycerols from the marine sponges {M}yrmekioderrna dendyi and {T}rikentrion laeve},
  author = {{F}arokhi, {F}. and {W}ielgosz-{C}ollin, {G}. and {R}obic, {A}. and {D}ebitus, {C}{\'e}cile and {M}alleter, {M}. and {R}oussakis, {C}. and {K}ornprobst, {J}. {M}. and {B}arnathan, {G}.},
  editor = {},
  language = {{ENG}},
  abstract = {{G}lycolipids of {M}yrmekioderma sponges contain {M}yrmekiosides, a new family of glycolipids with a unique structure of mono-{O}-alkyl-diglycosylglycerols. {T}his report deals with the identification and biological activity of the new {M}yrmekioside {E} from {M}yrmekioderma dendyi. {I}ts structure has been elucidated from spectroscopic data and chemical degradation studies. {I}t contained a glycerol backbone linked to xylose and {N}-acetylglucosamine, and an alkyl long-chain with a terminal alcohol group. {A} related glycolipid, {T}rikentroside, known in the sponge {T}rikentrion laeve, was subjected to a comparative biological evaluation. {B}oth glycolipids inhibit proliferation of two human non-small cell lung cancer cell lines ({NSCLC}-{N}6 and {A}549).},
  keywords = {{A}lkyldiglycosylglycerols ; {G}lycolipids ; {H}uman lung cancer ; {M}arine sponges ; {M}yrmekioderma ; {T}rikentrion},
  booktitle = {},
  journal = {{E}uropean {J}ournal of {M}edicinal {C}hemistry},
  volume = {49},
  numero = {},
  pages = {406--410},
  ISSN = {0223-5234},
  year = {2012},
  DOI = {10.1016/j.ejmech.2012.01.029},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00008873},
}