@article{PAR00008810,
  title = {{P}rimitive duplicate hox clusters in the {E}uropean eel's genome},
  author = {{H}enkel, {C}. {V}. and {B}urgerhout, {E}. and de {W}ijze, {D}. {L}. and {D}irks, {R}. {P}. and {M}inegishi, {Y}. and {J}ansen, {H}. {J}. and {S}paink, {H}. {P}. and {D}ufour, {S}ylvie and {W}eltzien, {F}. {A}. and {T}sukamoto, {K}. and van den {T}hillart, {G}. {E}. {E}. {J}. {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he enigmatic life cycle and elongated body of the {E}uropean eel ({A}nguilla anguilla {L}., 1758) have long motivated scientific enquiry. {R}ecently, eel research has gained in urgency, as the population has dwindled to the point of critical endangerment. {W}e have assembled a draft genome in order to facilitate advances in all provinces of eel biology. {H}ere, we use the genome to investigate the eel's complement of the {H}ox developmental transcription factors. {W}e show that unlike any other teleost fish, the eel retains fully populated, duplicate {H}ox clusters, which originated at the teleost-specific genome duplication. {U}sing m{RNA}-sequencing and in situ hybridizations, we demonstrate that all copies are expressed in early embryos. {T}heories of vertebrate evolution predict that the retention of functional, duplicate {H}ox genes can give rise to additional developmental complexity, which is not immediately apparent in the adult. {H}owever, the key morphological innovation elsewhere in the eel's life history coincides with the evolutionary origin of its {H}ox repertoire.},
  keywords = {{ATLANTIQUE} ; {NOUVELLE} {ZELANDE} ; {PAYS} {BAS} ; {SARGASSES} {MER}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {7},
  numero = {2},
  pages = {e32231},
  ISSN = {1932-6203},
  year = {2012},
  DOI = {10.1371/journal.pone.0032231},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00008810},
}