@article{PAR00007729, title = {{N}ationwide surveillance of 18 respiratory viruses in patients with influenza-like illnesses : a pilot feasibility study in the {F}rench {S}entinel {N}etwork}, author = {{F}alchi, {A}. and {T}urbelin, {C}. and {A}ndreoletti, {L}. and {A}rena, {C}. and {B}lanchon, {T}. and {B}onmarin, {I}. and {H}anslik, {T}. and {L}eruez-{V}ille, {M}. and de {L}amballerie, {X}avier and {C}arrat, {F}.}, editor = {}, language = {{ENG}}, abstract = {{T}he aim of the present study was to test the feasibility of integrating the diagnosis of 18 respiratory viruses into clinical surveillance of influenza-like illness using a {PCR}-{DNA} microarray detection assay. {T}he study took place in the {F}rench {S}entinel {N}etwork, a nationwide surveillance network of {G}eneral {P}ractitioners ({GP}s) representative of {F}rench {GP}s in terms age, location, and type of practice (urban/rural). {T}hree virological laboratories also participated in the study. {T}he study was planned for 5 weeks from {J}anuary 25, 2010 to {F}ebruary 27, 2010. {A} subset of 150 {S}entinel {GP}s, located in mainland {F}rance, was enrolled to collect clinical data and nasopharyngeal samples from every first patient of the week having a medical visit for influenza-like illness defined as a sudden fever of 39 {C} or more with respiratory symptoms and myalgia. {S}ixty-three {GP}s (42%) collected 103 samples while 87 {GP}s (58%) did not. {GP}s did not differ with respect to their age, gender, urban/rural distribution, or years of inscription in the {S}entinel {N}etwork. {P}atients included were of a similar age and had similar vaccination characteristics, but were more frequently men than influenza-like illness patients reported to the network during the study period. {S}ixty-one viruses were detected from 56 of 96 (58%) interpretable samples. {T}he respiratory viruses detected most frequently were metapneumovirus and respiratory syncytial virus. {T}his study showed that virological diagnosis of 18 respiratory viruses can be combined with surveillance of clinical influenza-like illness in general practice. {A}lthough feasibility has not been demonstrated yet, it will be evaluated over the winter of 2010-2011. {J}. {M}ed. {V}irol. 83:1451-1457, 2011.}, keywords = {respiratory viruses ; influenza-like illness ; surveillance system ; general practitioners}, booktitle = {}, journal = {{J}ournal of {M}edical {V}irology}, volume = {83}, numero = {8}, pages = {1451--1457}, ISSN = {0146-6615}, year = {2011}, DOI = {10.1002/jmv.22113}, URL = {https://www.documentation.ird.fr/hor/{PAR}00007729}, }