@article{PAR00006828, title = {{M}olecular epidemiology of yellow fever in {B}olivia from 1999 to 2008}, author = {{B}aronti, {C}{\'e}cile and {G}oitia, {N}.{J}.{V}. and {C}ook, {S}. and {R}oca, {Y}. and {R}evollo, {J}. and {F}lores, {J}.{V}. and {L}amballerie, {X}avier de}, editor = {}, language = {{ENG}}, abstract = {{Y}ellow fever ({YF}) is a serious public health problem in {B}olivia since at least the 19th century. {S}urprisingly, very limited information has been made available to date regarding the genetic characterisation and epidemiology of {B}olivian {YF} virus ({YFV}) strains. {H}ere, we conducted the genetic characterization of 12 human isolates of {YFV} collected in {B}olivia between 1999 and 2008, by sequencing and analysis of two regions of the viral genome: a fragment encoding structural proteins "{P}r{M}' (premembrane and envelope) and a distal region "{EMF},' spanning the end of the virus genome. {O}ur study reveals a high genetic diversity of {YFV} strains circulating in {B}olivia during the last decade: we identified not only "{P}eruvian-like' genotype {II} viruses (related to previously characterized {B}olivian strains), but also, for the fist time, "{B}razilian-like' genotype {I} viruses. {D}uring the complete period of the study, only cases of "jungle' {YF} were detected (i.e., circulation of {YFV} via a sylvatic cycle) with no cluster of urban cases. {H}owever, the very significant spread of the {A}edes aegypti mosquito across {B}olivian cities threatens the country with the reappearance of an urban {YFV} transmission cycle and thus is required a sustained epidemiological surveillance.}, keywords = {{A}edes ; {E}pidemiology ; {Y}ellow fever}, booktitle = {}, journal = {{V}ector-{B}orne and {Z}oonotic {D}iseases}, volume = {11}, numero = {3}, pages = {277--284}, ISSN = {1530-3667}, year = {2011}, DOI = {10.1089/vbz.2010.0017}, URL = {https://www.documentation.ird.fr/hor/{PAR}00006828}, }