@article{PAR00006125,
  title = {{P}ig liver sausage as a source of hepatitis {E} virus transmission to humans},
  author = {{C}olson, {P}. and {B}orentain, {P}. and {Q}ueyriaux, {B}. and {K}aba, {M}. and {M}oal, {V}. and {G}allian, {P}. and {H}eyries, {L}. and {R}aoult, {D}idier and {G}erolami, {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground. {T}he source and route of autochthonous hepatitis {E} virus ({HEV}) infections are not clearly established in industrialized countries despite evidence that it is a zoonosis in pigs. {W}e investigated the role of figatellu, a traditional pig liver sausage widely eaten in {F}rance and commonly consumed raw, as a source of {HEV} infection. {M}ethods. {A} case-control study was conducted of 3 patients who presented autochthonous hepatitis {E} and 15 members of their 3 different families. {A}nti-{HEV} immunoglobulin {G} and immunoglobulin {M} antibody testing was performed with commercial assays. {HEV} {RNA} was detected in serum samples of patients and in pig liver sausages by means of real-time polymerase chain reaction and sequenced by means of in-house sequencing assays. {G}enetic links between {HEV} sequences were analyzed. {R}esults. {A}cute or recent {HEV} infection, defined by detection of anti-{HEV} immunoglobulin {M} antibodies and/or {HEV} {RNA}, was observed in 7 of 13 individuals who ate raw figatellu and 0 of 5 individuals who did not eat raw figatellu ({P} = .041). {M}oreover, {HEV} {RNA} of genotype 3 was recovered from 7 of 12 figatelli purchased in supermarkets, and statistically significant genetic links were found between these sequences and those recovered from patients who ate raw figatellu. {C}onclusion. {O}ur findings strongly support the hypothesis of {HEV} infection through ingestion of raw figatellu.},
  keywords = {},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {202},
  numero = {6},
  pages = {825--834},
  ISSN = {0022-1899},
  year = {2010},
  DOI = {10.1086/655898},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00006125},
}