@article{PAR00004787, title = {{Z}oonotic aspects of arenavirus infections}, author = {{C}harrel, {R}. {N}. and de {L}amballerie, {X}avier}, editor = {}, language = {{ENG}}, abstract = {{T}o date, the {I}nternational {C}ommittee for {T}axonomy of {V}iruses recognizes that the family {A}renaviridae contains a unique genus {A}renavirus that includes 22 viral species. {T}here are nine additional arenaviruses that either have been discovered recently, or which taxonomic status remains pending. {A}renaviruses have been classified according to their antigenic properties into two groups, the {L}assa-{L}ymphocytic {C}horiomeningitis ({LCM}) serocomplex and the {T}acaribe serocomplex which has been further divided into four evolutionary lineages. {E}ach arenavirus is more or less tightly associated with a mammal host. {T}he distribution of the host dictates the distribution of the virus. {H}umans may become infected by arenaviruses through direct contact with infected rodents, including bites, or through inhalation of infectious rodent excreta and secreta. {L}assa, {J}unin, {M}achupo, {G}uanarito, and {S}abia viruses are known to cause a severe hemorrhagic fever, in western {A}frica, {A}rgentina, {B}olivia, {V}enezuela, and {B}razil, respectively. {I}nfection by {LCM} virus can result in acute central nervous system disease, congenital malformations, and infection in organ transplantation recipients. {D}etection of arenaviruses in their animal host can be achieved by virus isolation, and has recently taken advantage of {PCR}-based techniques. {T}he approach based on consensus degenerate primers has shown efficient for both detection of known arenaviruses, and discovery of new arenaviruses.}, keywords = {{A}renaviruses ; {Z}oonoses}, booktitle = {}, journal = {{V}eterinary {M}icrobiology}, volume = {140}, numero = {3-4}, pages = {213--220}, ISSN = {0378-1135}, year = {2010}, DOI = {10.1016/j.vetmic.2009.08.027}, URL = {https://www.documentation.ird.fr/hor/{PAR}00004787}, }