@article{PAR00004561,
  title = {{G}iant {M}arseillevirus highlights the role of amoebae as a melting pot in emergence of chimeric microorganisms},
  author = {{B}oyer, {M}. and {Y}utin, {N}. and {P}agnier, {I}. and {B}arrassi, {L}. and {F}ournous, {G}. and {E}spinosa, {L}. and {R}obert, {C}. and {A}zza, {S}. and {S}un, {S}. {Y}. and {R}ossmann, {M}. {G}. and {S}uzan-{M}onti, {M}. and {L}a {S}cola, {B}. and {K}oonin, {E}. {V}. and {R}aoult, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{G}iant viruses such as {M}imivirus isolated from amoeba found in aquatic habitats show biological sophistication comparable to that of simple cellular life forms and seem to evolve by similar mechanisms, including extensive gene duplication and horizontal gene transfer ({HGT}), possibly in part through a viral parasite, the virophage. {W}e report here the isolation of "{M}arseille' virus, a previously uncharacterized giant virus of amoeba. {T}he virions of {M}arseillevirus encompass a 368-kb genome, a minimum of 49 proteins, and some messenger {RNA}s. {P}hylogenetic analysis of core genes indicates that {M}arseillevirus is the prototype of a family of nucleocytoplasmic large {DNA} viruses ({NCLDV}) of eukaryotes. {T}he genome repertoire of the virus is composed of typical {NCLDV} core genes and genes apparently obtained from eukaryotic hosts and their parasites or symbionts, both bacterial and viral. {W}e propose that amoebae are "melting pots' of microbial evolution where diverse forms emerge, including giant viruses with complex gene repertoires of various origins.},
  keywords = {giant virus ; horizontal gene transfer ; nucleocytoplasmic large {DNA} ; virus ; viral evolution},
  booktitle = {},
  journal = {{P}roceedings of the {N}ational {A}cademy of {S}ciences of the {U}nited {S}tates of {A}merica},
  volume = {106},
  numero = {51},
  pages = {21848--21853},
  ISSN = {0027-8424},
  year = {2009},
  DOI = {10.1073/pnas.0911354106},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00004561},
}