@article{PAR00003858, title = {{M}olecular epidemiological analysis of dengue fever in {B}olivia from 1998 to 2008}, author = {{R}oca, {Y}. and {B}aronti, {C}{\'e}cile and {R}evollo, {R}. {J}. and {C}ook, {S}. and {L}oayza, {R}. and {N}inove, {L}. and {F}ernandez, {R}. {T}. and {F}lores, {J}.{V}. and {H}erv{\'e}, {J}ean-{P}ierre and {L}amballerie, {X}avier de}, editor = {}, language = {{ENG}}, abstract = {{D}engue fever was first recognized in {B}olivia in 1931. {H}owever, very limited information was available to date regarding the genetic characterization and epidemiology of {B}olivian dengue virus strains. {H}ere, we performed genetic characterization of the full-length envelope gene of 64 {B}olivian isolates from 1998 to 2008 and investigated their origin and evolution to determine whether strains circulated simultaneously or alternatively, and whether or not multiple introductions of distinct viral variants had occurred during the period studied. {W}e determined that, during the last decade, closely related viruses circulated during several consecutive years (5, 6, and 6 years for {DENV}-1, {DENV}-2, and {DENV}-3, respectively) and the co-circulation of two or even three serotypes was observed. {E}mergence of new variants (distinct from those identified during the previous episodes) was identified in the case of {DENV}-1 (2007 outbreak) and {DENV}-2 (2001 outbreak). {I}n all cases, it is likely that the viruses originated from neighboring countries.}, keywords = {{D}engue ; {E}pidemiology ; {G}enetics}, booktitle = {}, journal = {{V}ector-{B}orne and {Z}oonotic {D}iseases}, volume = {9}, numero = {3}, pages = {337--344}, ISSN = {1530-3667}, year = {2009}, DOI = {10.1089/vbz.2008.0187}, URL = {https://www.documentation.ird.fr/hor/{PAR}00003858}, }