@article{PAR00003786,
  title = {{M}olecular detection of divergent trypanosomes among rodents in {T}hailand},
  author = {{J}ittapalapong, {S}. and {I}npankaew, {T}. and {S}arataphan, {N}. and {H}erbreteau, {V}incent and {H}ugot, {J}ean-{P}ierre and {M}orand, {S}erge and {S}tich, {R}.{W}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}erpetosoma is a homogenous subgenus of several dozen named species that are often described as morphologically indistinguishable {T}. lewisi-like parasites. {T}hese trypanosomes normally infect rodents and utilize fleas as vectors. {A}lthough this trypanosome subgenus is considered non-pathogenic to normal hosts, some of them are on rare occasion reported in association with human disease. {R}ecently, a {T}. lewisi-like infection was detected in a sick {T}hai infant, thus the objective of this study was to investigate the prevalence of {T}. lewisi infections among different rodents indigenous to {T}hailand in order to identify possible sources of human cases. {B}lood was collected from a total of 276 rodents trapped from urban and rural areas of three {T}hai provinces between 2006 and 2007. {T}hese samples were processed for {DNA} isolation and tested with a {PCR} assay universal for the genus {T}rypanosoma, followed by internal transcribed spacer 1 ({ITS}-1) sequence analysis to identify infections in positive samples. {H}erpetosoma known as {T}. lewisi-like trypanosomes were present among {R}attus (14.3%) and {B}andicota (18.0%) rodent species and salivarian trypanosomes closely related to {T}. evansi were detected in {L}eopoldamys (20%) and {R}attus (2.0%) species. {H}erpetosoma were prevalent among rodents associated with both human and sylvatic habitats, while three of the four salivaria-positive rodents were from a forest biotope. {A} {H}erpetosoma {ITS}-1 sequence amplified from one of these samples was 97.9% identical to that reported for {T}. lewisi in an experimentally infected rat and 96.4% identical to the sequence amplified from blood from a {T}hai infant. {H}abitats where rodents were collected significantly affect rodent infection, at least for {T}. lewisi, suggesting that the degree of anthropization may influence the transmission of {T}rypanosoma spp. {T}hese results suggest that multiple {H}erpetosoma species or strains are enzootic to {T}hailand, and that {R}attus and {B}andicota species are possible sources of human exposure to these parasites.},
  keywords = {{THAILANDE}},
  booktitle = {},
  journal = {{I}nfection {G}enetics and {E}volution},
  volume = {8},
  numero = {4},
  pages = {445--449},
  ISSN = {1567-1348},
  year = {2008},
  DOI = {10.1016/j.meegid.2007.08.002 },
  URL = {https://www.documentation.ird.fr/hor/{PAR}00003786},
}