@article{PAR00003352, title = {{O}rigins and genetic diversity of pygmy hunter-gatherers from western central africa}, author = {{V}erdu, {P}. and {A}usterlitz, {F}. and {E}stoup, {A}. and {V}italis, {R}. and {G}eorges, {M}. and {T}hery, {S}. and {F}roment, {A}lain and {L}e {B}omin, {S}. and {G}essain, {A}. and {H}ombert, {J}. {M}. and {V}an der {V}een, {L}. and {Q}uintana {M}urci, {L}. and {B}ahuchet, {S}. and {H}eyer, {E}.}, editor = {}, language = {{ENG}}, abstract = {{C}entral {A}frica is currently peopled by numerous sedentary agriculturalist populations neighboring the largest group of mobile hunter-gatherers, the {P}ygmies [1-3]. {A}lthough archeological remains attest to {H}omo sapiens' presence in the {C}ongo {B}asin for at least 30,000 years, the demographic history of these groups, including divergence and admixture, remains widely unknown [4-6]. {M}oreover, it is still debated whether common history or convergent adaptation to a forest environment resulted in the short stature characterizing the pygmies [2,7]. {W}e genotyped 604 individuals at 28 autosomal tetranucleotide microsatellite loci in 12 nonpygmy and 9 neighboring pygmy populations. {W}e found a high level of genetic heterogeneity among {W}estern {C}entral {A}frican pygmies, as well as evidence of heterogeneous levels of asymmetrical gene flow from nonpygmies to pygmies, consistent with the variable sociocultural barriers against intermarriages. {U}sing approximate {B}ayesian computation ({ABC}) methods [8], we compared several historical scenarios. {T}he most likely points toward a unique ancestral pygmy population that diversified similar to 2800 years ago, contemporarily with the {N}eolithic expansion of nonpygmy agriculturalists [9, 10]. {O}ur results show that recent isolation, genetic drift, and heterogeneous admixture enabled a rapid and substantial genetic differentiation among {W}estern {C}entral {A}frican pygmies. {S}uch an admixture pattern is consistent with the various sociocultural behaviors related to intermariages between pygmies and nonpygmies.}, keywords = {{AFRIQUE} {CENTRALE} ; {CONGO} {BASSIN}}, booktitle = {}, journal = {{C}urrent {B}iology}, volume = {19}, numero = {4}, pages = {312--318}, ISSN = {0960-9822}, year = {2009}, DOI = {10.1016/j.cub.2008.12.049}, URL = {https://www.documentation.ird.fr/hor/{PAR}00003352}, }