<?xml version="1.0" encoding="UTF-8"?>
<modsCollection xmlns="http://www.loc.gov/mods/v3" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd">
  <mods>
    <titleInfo>
      <title>Virulence and resistance in malaria : who drives the outcome of the infection?</title>
    </titleInfo>
    <name type="personnal">
      <namePart type="family">Lefèvre</namePart>
      <namePart type="given">Thierry</namePart>
      <role>
        <roleTerm type="text">auteur</roleTerm>
        <roleTerm type="code" authority="marcrelator">aut</roleTerm>
      </role>
      <affiliation>IRD</affiliation>
    </name>
    <name type="personnal">
      <namePart type="family">Sanchez</namePart>
      <namePart type="given">Marta</namePart>
      <role>
        <roleTerm type="text">auteur</roleTerm>
        <roleTerm type="code" authority="marcrelator">aut</roleTerm>
      </role>
      <affiliation>IRD</affiliation>
    </name>
    <name type="personnal">
      <namePart type="family">Ponton</namePart>
      <namePart type="given">Fleur</namePart>
      <role>
        <roleTerm type="text">auteur</roleTerm>
        <roleTerm type="code" authority="marcrelator">aut</roleTerm>
      </role>
      <affiliation>IRD</affiliation>
    </name>
    <name type="personnal">
      <namePart type="family">Hughes</namePart>
      <namePart type="given">D.</namePart>
      <role>
        <roleTerm type="text">auteur</roleTerm>
        <roleTerm type="code" authority="marcrelator">aut</roleTerm>
      </role>
      <affiliation>IRD</affiliation>
    </name>
    <name type="personnal">
      <namePart type="family">Thomas</namePart>
      <namePart type="given">F.</namePart>
      <role>
        <roleTerm type="text">auteur</roleTerm>
        <roleTerm type="code" authority="marcrelator">aut</roleTerm>
      </role>
      <affiliation>IRD</affiliation>
    </name>
    <typeOfResource>text</typeOfResource>
    <genre authority="local">journalArticle</genre>
    <language>
      <languageTerm type="code" authority="iso639-2b">eng</languageTerm>
    </language>
    <physicalDescription>
      <internetMediaType>text/pdf</internetMediaType>
      <digitalOrigin>born digital</digitalOrigin>
      <reformattingQuality>access</reformattingQuality>
    </physicalDescription>
    <abstract>Theoretical and experimental studies have established the dynamic nature of virulence and that, like all traits, it has evolved. Understanding parasite evolution offers a conceptual framework for diverse fields and can contribute greatly to decision-making in disease control. Recently, Grech et al. investigated the effects of host genotype-by-parasite genotype interactions on the expression of virulence in an artificial rodent-malaria system. They found that both parasite and host effects explained most of the variance in the virulence, resistance and transmission potential. These findings are a major contribution to the emerging debate on the pros and cons of a coevolutionary approach of virulence evolution; they also hold great potential for more effective control strategies.</abstract>
    <targetAudience authority="marctarget">specialized</targetAudience>
    <classification authority="local">052</classification>
    <relatedItem type="host">
      <titleInfo>
        <title>Trends in Parasitology</title>
      </titleInfo>
      <part>
        <detail type="volume">
          <number>23</number>
        </detail>
        <detail type="volume">
          <number>7</number>
        </detail>
        <extent unit="pages">
          <list> 299-302</list>
        </extent>
      </part>
      <originInfo>
        <dateIssued>2007</dateIssued>
      </originInfo>
      <identifier type="issn">1471-4922</identifier>
    </relatedItem>
    <identifier type="uri">https://www.documentation.ird.fr/hor/PAR00001829</identifier>
    <identifier type="doi">10.1016/j.pt.2007.04.012</identifier>
    <identifier type="issn">1471-4922</identifier>
    <location>
      <shelfLocator>[F B010040702]</shelfLocator>
      <url usage="primary display" access="object in context">https://www.documentation.ird.fr/hor/PAR00001829</url>
      <url access="row object">https://www.documentation.ird.fr/intranet/publi/2007/09/010040702.pdf</url>
    </location>
    <accessCondition type="restriction access" displayLabel="Accès réservé">Accès réservé (Intranet de l'IRD)</accessCondition>
    <recordInfo>
      <recordContentSource>IRD - Base Horizon / Pleins textes</recordContentSource>
      <recordCreationDate encoding="w3cdtf">2007-10-11</recordCreationDate>
      <recordChangeDate encoding="w3cdtf">2017-08-23</recordChangeDate>
      <recordIdentifier>PAR00001829</recordIdentifier>
      <languageOfCataloging>
        <languageTerm authority="iso639-2b">fre</languageTerm>
      </languageOfCataloging>
    </recordInfo>
  </mods>
</modsCollection>
