Horizon 1 1 17 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES Trends in Parasitology 299-302 2007 PAR00001829 ENG Trends in Parasitology 1471-4922 CC:0002479630-0003 7 10.1016/j.pt.2007.04.012 https://www.documentation.ird.fr/hor/PAR00001829 https://www.documentation.ird.fr/intranet/publi/2007/09/010040702.pdf 23 Horizon (IRD) Theoretical and experimental studies have established the dynamic nature of virulence and that, like all traits, it has evolved. Understanding parasite evolution offers a conceptual framework for diverse fields and can contribute greatly to decision-making in disease control. Recently, Grech et al. investigated the effects of host genotype-by-parasite genotype interactions on the expression of virulence in an artificial rodent-malaria system. They found that both parasite and host effects explained most of the variance in the virulence, resistance and transmission potential. These findings are a major contribution to the emerging debate on the pros and cons of a coevolutionary approach of virulence evolution; they also hold great potential for more effective control strategies. 052