Virulence and resistance in malaria : who drives the outcome of the infection? Lefèvre, Thierry Sanchez, Marta Ponton, Fleur Hughes, D. Thomas, F. Theoretical and experimental studies have established the dynamic nature of virulence and that, like all traits, it has evolved. Understanding parasite evolution offers a conceptual framework for diverse fields and can contribute greatly to decision-making in disease control. Recently, Grech et al. investigated the effects of host genotype-by-parasite genotype interactions on the expression of virulence in an artificial rodent-malaria system. They found that both parasite and host effects explained most of the variance in the virulence, resistance and transmission potential. These findings are a major contribution to the emerging debate on the pros and cons of a coevolutionary approach of virulence evolution; they also hold great potential for more effective control strategies. 2007 text https://www.documentation.ird.fr/hor/PAR00001829 PAR00001829 Lefèvre Thierry, Sanchez Marta, Ponton Fleur, Hughes D., Thomas F.. Virulence and resistance in malaria : who drives the outcome of the infection?. 2007, 23 (7), 299-302 EN