@article{PAR00001829, title = {{V}irulence and resistance in malaria : who drives the outcome of the infection?}, author = {{L}ef{\`e}vre, {T}hierry and {S}anchez, {M}arta and {P}onton, {F}leur and {H}ughes, {D}. and {T}homas, {F}.}, editor = {}, language = {{ENG}}, abstract = {{T}heoretical and experimental studies have established the dynamic nature of virulence and that, like all traits, it has evolved. {U}nderstanding parasite evolution offers a conceptual framework for diverse fields and can contribute greatly to decision-making in disease control. {R}ecently, {G}rech et al. investigated the effects of host genotype-by-parasite genotype interactions on the expression of virulence in an artificial rodent-malaria system. {T}hey found that both parasite and host effects explained most of the variance in the virulence, resistance and transmission potential. {T}hese findings are a major contribution to the emerging debate on the pros and cons of a coevolutionary approach of virulence evolution; they also hold great potential for more effective control strategies.}, keywords = {}, booktitle = {}, journal = {{T}rends in {P}arasitology}, volume = {23}, numero = {7}, pages = {299--302}, ISSN = {1471-4922}, year = {2007}, DOI = {10.1016/j.pt.2007.04.012}, URL = {https://www.documentation.ird.fr/hor/{PAR}00001829}, }