Da Lage J. L. auteur aut IRD Kergoat G. J. auteur aut IRD Maczkowiak F. auteur aut IRD Silvain Jean-François auteur aut IRD Cariou M. L. auteur aut IRD Lachaise D. auteur aut IRD text journalArticle eng text/pdf born digital access In this study, the phylogenetic relationships of 164 species of the family Drosophilidae are discussed, using the Amyrel gene, a member of the alpha-amylase multigene family. This study focuses on numerous species groups in the subgenera Sophophora and Drosophila of the genus Drosophila but also includes other closely related genera. Nucleotide data were analysed by several methods: maximum parsimony, neighbour joining, maximum likelihood and Bayesian inference. Heterogeneity of base composition (mainly low GC contents in the species groups willistoni and saltans) has been addressed. In all analyses, the genus Drosophila appeared paraphyletic. The subgenus Sophophora clearly appeared to be a monophyletic group, showing well-resolved clades, with the Neotropical groups arising in a basal position. Here, it is proposed to raise the species subgroups ananassae and montium to the rank of species group, and to restrict the melanogaster species group to the melanogaster subgroup plus the 'Oriental' subgroups, among which the suzukii subgroup is polyphyletic. Some related genera such as Zaprionus, Liodrosophila, Scaptomyza and Hirtodrosophila are clustered with, or inside the subgenus Drosophila, which is therefore paraphyletic and should be reviewed. specialized molecular phylogeny Zaprionus ananassae species group montium species group base composition bias Sophophora 080 45 1 47-63 2007 0947-5745 https://www.documentation.ird.fr/hor/PAR00001475 10.1111/j.1439-0469.2006.00389.x 0947-5745 [F A010037820] https://www.documentation.ird.fr/hor/PAR00001475 https://www.documentation.ird.fr/intranet/publi/2007/03/010037820.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2007-03-30 2017-08-23 PAR00001475 fre