@article{PAR00000396,
  title = {{L}ongitudinal assessment of {HIV}-1 and {HSV}-2 shedding in the genital tract of {W}est {A}frican women},
  author = {{N}agot, {N}. and {F}oulongne, {V}. and {B}ecquart, {P}. and {M}ayaud, {P}. and {K}onate, {I}. and {O}uedraogo, {A}. and {D}efer, {M}. {C}. and {W}eiss, {H}. and {V}an de {P}erre, {P}. and {S}egondy, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{F}orty-two {HSV}-2-seropositive women, of whom 22 were {HIV}-1 seropositive, were followed up weekly for 3 weeks for assessment of {HIV}-1 and {HSV}-2 genital shedding in {B}obo {D}ioulasso, {B}urkina {F}aso. {HSV}-2 {DNA} and {HIV}-1 {RNA} were quantitated in cervicovaginal lavages enriched with a cervical swabbing (e{CVL}) using real-time polymerase chain reaction. {HIV}-1 {RNA} shedding was detected in e{CVL} from 19 of 22 (86.4%) of the {HIV}-1-seropositive women and {HSV}-2 {DNA} was detected in e{CVL} from 12 of 42 (28.6%) of the women. {C}ompared with the {HIV}-1-seronegative women, the {HIV}-1-seropositive women showed more persistent {HSV}-2 genital shedding and higher {HSV}-2 {DNA} loads in e{CVL}. {T}his study showed that e{CVL} is a reliable sampling method for detecting both viruses. {T}hree measurement points (at weekly intervals in this study) seem to adequately allow detection of most {HIV}-1 or {HSV}-2 genital shedders.},
  keywords = {{HIV} 1 {RNA} ; {HSV} 2 {DNA} ; genital shedding ; {A}frican women},
  booktitle = {},
  journal = {{J}aids {J}ournal of {A}cquired {I}mmune {D}eficiency {S}yndromes},
  volume = {39},
  numero = {5},
  pages = {632--634},
  ISSN = {1525-4135},
  year = {2005},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00000396},
}