@article{PAR00000340, title = {{A}cylphloroglucinol derivatives from {M}ahurea palustris}, author = {{M}assiot, {G}. and {L}ong, {C}. and {D}avid, {B}. and {S}errano, {M}. {J}. and {D}aubie, {F}. and {A}lby, {F}. and {A}usseil, {F}. and {K}nibiehler, {M}. and {M}oretti, {C}. and {H}offmann, {J}. {S}. and {C}azaux, {C}. and {L}avaud, {C}.}, editor = {}, language = {{ENG}}, abstract = {{F}ive new acylphloroglucinol derivatives, mahureones {A}-{E} (1, 3-6), have been isolated from the leaves of {M}ahurea palustris, and their structures determined by spectroscopic means. {D}uring the isolation process, several byproducts (7-9) were formed by reaction of one of the isoprenyl side chains with {TFA}, water, and acetonitrile. {A}ll the compounds were assayed for their ability to inhibit human {DNA} polymerase beta. {T}he most active compounds, mahureones {A} (1) and {D} (5), exhibited {IC}50 values in the 10 mu {M} range.}, keywords = {}, booktitle = {}, journal = {{J}ournal of {N}atural {P}roducts}, volume = {68}, numero = {7}, pages = {979--984}, ISSN = {0163-3864}, year = {2005}, DOI = {10.1021/np049676o}, URL = {https://www.documentation.ird.fr/hor/{PAR}00000340}, }