D'Auria V., Paloma L.G., Minale L., Zampella A., Verbist J.F., Roussakis C., Debitus Cécile. (1993). Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge Neosiphonia superstes. Tetrahedron, 49 (38), p. 8657-8664. ISSN 0040-4020.
Titre du document
Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge Neosiphonia superstes
Tetrahedron, 1993,
49 (38), p. 8657-8664 ISSN 0040-4020
Three new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge N. superstes collected off New Caledonia. The structures of the new compounds were determined by interpretation of NMR spectral data as well as comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells. (Résumé d'auteur)