@article{fdi:34102,
  title = {{I}solement et synth{\`e}se de l'espintanol, nouveau monoterp{\`e}ne antiparasitaire},
  author = {{H}ocquemiller, {R}. and {C}ortes, {D}. and {A}rango, {G}.{J}. and {M}yint, {S}.{H}. and {C}av{\'e}, {A}. and {A}ngelo, {A}. and {M}unoz, {V}. and {F}ournet, {A}lain},
  editor = {},
  language = {{FRE}},
  abstract = {{T}he in vitro leishmanicidal and trypanocidal activities of a petroleum ether extract of #{O}xandra espintana$ have been investigated. {F}our aromatic monoterpenes were isolated, of which two are novel : espintanol (3a), responsible for the antiparasite activity, and {O}-methylespintanol (4). {E}spintanol was tested in vitro on 20 strains of #{T}rypanosoma cruzi$ and 12 strains of #{L}eishmania$ spp. {I}ts structure was determined by spectroscopic methods and confirmed by its preparation starting from carvacrol. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{MALADIE} {DE} {CHAGAS} ; {LEISHMANIOSE} ; {ETUDE} {COMPARATIVE} ; {ACTIVITE} {BIOLOGIQUE} ; {EXPERIMENTATION} {IN} {VITRO} ; {SUBSTANCE} {NATURELLE} ; {MONOTERPENE} ; {ESPINTANOL} ; {PROMASTIGOTE} ; {AMASTIGOTE} ; {SOUCHE} {TYPIFIEE} ; {BOLIVIE}},
  booktitle = {},
  journal = {{J}ournal of {N}atural {P}roducts},
  volume = {54},
  numero = {2},
  pages = {445--452},
  ISSN = {0163-3864},
  year = {1991},
  DOI = {10.1021/np50074a015},
  URL = {https://www.documentation.ird.fr/hor/fdi:34102},
}