@article{fdi:25506,
  title = {{T}hymulin (facteur thymique s{\'e}rique) and zinc contents of the thymus glands of malnourished children},
  author = {{J}ambon, {B}ernard and {Z}iegler, {O}. and {M}aire, {B}ernard and {H}utin, {M}.{F}. and {P}arent, {G}{\'e}rard and {F}all, {M}. and {B}urnel, {D}. and {D}uheille, {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{P}rotein-energy malnutrition ({PEM}) leads to an immune deficiency, which is now well documented. {S}ome investigators have suggested that the associated zinc deficiency is important in thymic involution and changes in cellular immunity. {T}o evaluate the respective roles of nutritional deficiency, infection, and zinc in the alteration of thymic function, we measured the amounts of thymulin (facteur thymique s{\'e}rique, or {FTS}) and of {Z}n in the thymus glands of 58 {S}enegalese children who died in various stages of malnutrition. {I}n the severe forms (marasmus, kwashiorkor, and marasmic kwashiorkor) the thymus was tiny and contained very little thymulin. {T}he {Z}n content of the thymus was high whatever the nutritional state of the subject and was related significantly only to the presence of infections. {I}n {S}enegalese children thymic atrophy and depleted thymulin content are associated with severe {PEM} but not systemic infection or depleted thymic {Z}n content. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{ENFANT} {D}'{AGE} {PRESCOLAIRE} ; {MALNUTRITION} {PROTEINOENERGETIQUE} ; {INFECTION} ; {ZINC} ; {FACTEUR} {THYMIQUE} {SERIQUE} ; {THYMULINE} ; {THYMUS} ; {IMMUNODEFICIENCE} ; {SENEGAL} ; {DAKAR}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {C}linical {N}utrition},
  volume = {48},
  numero = {2},
  pages = {335--342},
  ISSN = {0002-9165},
  year = {1988},
  URL = {https://www.documentation.ird.fr/hor/fdi:25506},
}